SCT066
BioTracker Tau filaments pFTAA Live Cell Dye
Sinônimo(s):
Live cell imaging probe
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About This Item
Código UNSPSC:
12171501
NACRES:
NA.32
Produtos recomendados
técnica(s)
cell based assay: suitable
Descrição geral
Protein misfolding diseases are characterized by deposition of protein aggregates. Accumulation of protein deposits, so-called amyloid, is the histopathological hallmark of several devastating diseases, and the development of sensitive optical ligands to detect and characterize these disease-associated structures is of great interest.
The BioTracker Tau filaments pFTAA live cell dye is a novel fluorescent probe that can bind to and discriminate between amyloid-b (A?) plaques and tau neurofibrillary tangles (NFTs) in Alzheimer′s disease (AD)-like pathology in transgenic mouse brain tissue sections.
Spectral Properties:
References:
Klingstedt T et al. The Structural Basis for Optimal Performance of Oligothiophene-Based Fluorescent Amyloid Ligands: Conformational Flexibility is Essential for Spectral Assignment of a Diversity of Protein Aggregates. Chem Eur J. 2013, 19, 10179-10192.
The BioTracker Tau filaments pFTAA live cell dye is a novel fluorescent probe that can bind to and discriminate between amyloid-b (A?) plaques and tau neurofibrillary tangles (NFTs) in Alzheimer′s disease (AD)-like pathology in transgenic mouse brain tissue sections.
Spectral Properties:
- Excitation: 405 nm
- Emissions: 550 nm
References:
Klingstedt T et al. The Structural Basis for Optimal Performance of Oligothiophene-Based Fluorescent Amyloid Ligands: Conformational Flexibility is Essential for Spectral Assignment of a Diversity of Protein Aggregates. Chem Eur J. 2013, 19, 10179-10192.
Aplicação
Application: Live cell fluorescent imaging
Live cell imaging dye for detection of disease-associated protein aggregates such as Amyloid protein deposits.
Qualidade
Purity: ≥98% confirmed by HNMR, LC-MS and HPLC and elemental analysis
Molar Mass: 704.65 g/mol
Molar Mass: 704.65 g/mol
Outras notas
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial
Código de classe de armazenamento
13 - Non Combustible Solids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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