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Documentos Principais

MAB2022

Sigma-Aldrich

Anti-Keratan Sulfate Antibody, clone EFG-11

ascites fluid, clone EFG-11, Chemicon®

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Preço e disponibilidade não estão disponíveis no momento.

fonte biológica

mouse

Nível de qualidade

forma do anticorpo

ascites fluid

clone

EFG-11, monoclonal

reatividade de espécies

sheep, bovine, pig, canine, mouse, human

fabricante/nome comercial

Chemicon®

técnica(s)

ELISA: suitable
radioimmunoassay: suitable
western blot: suitable

Isotipo

IgG2b

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

dry ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... LUM(4060)

Especificidade

Recognizes 2-3 disaccharide units on both skeletal (type II) and corneal (type I) keratan sulfate chains either in isolated or proteoglycan-bound form. The epitope is resistant to proteolytic or alkaline cleavages and partially sensitive to keratanase or other endo-B-galactosidase treatment.

Imunogênio

Human articular cartilage proteoglycan digested with chondroitinase ABC.

Aplicação

Anti-Keratan Sulfate Antibody, clone EFG-11 is an antibody against Keratan Sulfate for use in ELISA, RIA & WB.
Research Category
Cell Structure
Research Sub Category
Cytokeratins
Western blot at 1:1000 - 1:4000

ELISA at 1:5,000-1:20,000

RIA at 1:30,000-1:500,000

May be used in a competitive inhibition assay to measure keratan sulfate levels.

forma física

Ascites liquid, no preservative.

Armazenamento e estabilidade

Maintain at -20°C in convenient aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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Monoclonal antibodies to different protein-related epitopes of human articular cartilage proteoglycans.
Glant, T T, et al.
The Biochemical Journal, 234, 31-41 (1986)
G Cs-Szabó et al.
Arthritis and rheumatism, 38(5), 660-668 (1995-05-01)
To identify characteristic changes in large aggregating (aggrecan) and small proteoglycan (PG) populations in articular cartilages during osteoarthritis (OA) and rheumatoid arthritis (RA). Aggrecan populations in guanidine extracts of femoral condylar cartilages of 46 OA and 8 RA patients who
Proteoglycan epitopes as potential markers of normal and pathologic cartilage metabolism.
V C Hascall et al.
Arthritis and rheumatism, 30(5), 586-588 (1987-05-01)
Jesús-José Ferre-Fernández et al.
Human genomics, 16(1), 49-49 (2022-10-27)
FOXC1 encodes a forkhead-domain transcription factor associated with several ocular disorders. Correct FOXC1 dosage is critical to normal development, yet the mechanisms controlling its expression remain unknown. Together with FOXQ1 and FOXF2, FOXC1 is part of a cluster of FOX
Xinping C Zhao et al.
Investigative ophthalmology & visual science, 47(10), 4341-4348 (2006-09-28)
To evaluate the zebrafish as a model for the studies of corneal development and disease. Zebrafish embryos and larvae at various stages of development were used for documenting corneal morphogenesis and differentiation. Corneal samples were collected from embryos, larvae, and

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