Recognizes 2-3 disaccharide units on both skeletal (type II) and corneal (type I) keratan sulfate chains either in isolated or proteoglycan-bound form. The epitope is resistant to proteolytic or alkaline cleavages and partially sensitive to keratanase or other endo-B-galactosidase treatment.
Imunogênio
Human articular cartilage proteoglycan digested with chondroitinase ABC.
Aplicação
Anti-Keratan Sulfate Antibody, clone EFG-11 is an antibody against Keratan Sulfate for use in ELISA, RIA & WB.
Research Category Cell Structure
Research Sub Category Cytokeratins
Western blot at 1:1000 - 1:4000
ELISA at 1:5,000-1:20,000
RIA at 1:30,000-1:500,000
May be used in a competitive inhibition assay to measure keratan sulfate levels.
forma física
Ascites liquid, no preservative.
Armazenamento e estabilidade
Maintain at -20°C in convenient aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Informações legais
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Arthritis and rheumatism, 38(5), 660-668 (1995-05-01)
To identify characteristic changes in large aggregating (aggrecan) and small proteoglycan (PG) populations in articular cartilages during osteoarthritis (OA) and rheumatoid arthritis (RA). Aggrecan populations in guanidine extracts of femoral condylar cartilages of 46 OA and 8 RA patients who
Proteoglycan epitopes as potential markers of normal and pathologic cartilage metabolism.
V C Hascall et al.
Arthritis and rheumatism, 30(5), 586-588 (1987-05-01)
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