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IM37

Sigma-Aldrich

Anti-MMP-9 (Ab-3) Mouse mAb (56-2A4)

liquid, clone 56-2A4, Calbiochem®

Sinônimo(s):

Anti-Gelatinase B, Anti-92 kDa Gelatinase, Anti-Matrix Metalloproteinase 9

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

mouse

Nível de qualidade

forma do anticorpo

purified antibody

tipo de produto de anticorpo

primary antibodies

clone

56-2A4, monoclonal

forma

liquid

contém

≤0.1% sodium azide as preservative

reatividade de espécies

human, rabbit, rat, guinea pig

não deve reagir com

hamster, mouse, bovine

fabricante/nome comercial

Calbiochem®

condição de armazenamento

OK to freeze
avoid repeated freeze/thaw cycles

Isotipo

IgG1

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... MMP9(4318)

Descrição geral

Purified mouse monoclonal antibody (see application references). Recognizes both the ~92 kDa latent and the ~83 kDa active forms of MMP-9.
Recognizes the ~92 kDa latent and the ~83 kDa active forms of MMP-9 in breast carcinoma tissue.
This Anti-MMP-9 (Ab-3) Mouse mAb (56-2A4) is validated for use in Frozen Sections, Immunoblotting, Paraffin Sections for the detection of MMP-9 (Ab-3).

Imunogênio

Human
a synthetic peptide corresponding to amino acids 626-644 of human MMP-9

Aplicação


Frozen Sections (see application references)
Immunoblotting (1 g/ml)
Paraffin Sections (see application references)

Embalagem

Please refer to vial label for lot-specific concentration.

Advertência

Toxicity: Standard Handling (A)

forma física

In 100 mM sodium phosphate buffer, 0.1% BSA, pH 7.0

Reconstituição

Following initial thaw, aliquot and freeze (-20°C).

Nota de análise

Negative Control
MMP-2 protein (Cat. Nos. PF023 or PF037)
Positive Control
MMP-9 protein (Cat. Nos. PF024 or PF038) or breast carcinoma tissue

Outras notas

Cottam, D.W. and Rees, R.C. 1993. Intl. J. Oncol.2, 861.
Stetler-Stevenson, W.G., et al. 1993. FASEB J.7, 1434.
Okada, Y., et al., 1992. J. Biol. Chem.267, 21712.
Woessner, J.F. 1991. FASEB J.5, 2145.
Liotta, L.A. and Stetler-Stevenson, W.G. 1990. in Seminars in Cancer Biology, ed. M.M. Gottesman. Vol. 1, 99.
This antibody does not react with MMP-1, MMP-2, MMP-3 or MMP-13. Antibody should be titrated for optimal results in individual systems.

Informações legais

Manufactured by Daiichi Fine Chemical Co., Ltd. Not available for sale in Japan.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Nezam Haider et al.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 16(5), 753-762 (2009-08-08)
Macrophage apoptosis and MMP activity contribute to vulnerability of atherosclerotic plaques to rupture. By employing molecular imaging techniques, we investigated if apoptosis and MMP release are interlinked. Atherosclerosis was produced in rabbits receiving high-cholesterol diet (HC), who underwent dual radionuclide
Shinichiro Fujimoto et al.
Journal of the American College of Cardiology, 52(23), 1847-1857 (2008-11-29)
This study sought to evaluate the feasibility of noninvasive detection of matrix metalloproteinase (MMP) activity in experimental atherosclerosis using technetium-99m-labeled broad matrix metalloproteinase inhibitor (MPI) and to determine the effect of dietary modification and statin treatment on MMP activity. The
Satoru Ohshima et al.
Journal of the American College of Cardiology, 55(12), 1240-1249 (2010-03-20)
Technetium-99m-labeled matrix metalloproteinase inhibitor (MPI) was used for the noninvasive assessment of matrix metalloproteinase (MMP) activity in atherosclerotic plaques after minocycline (MC) intervention. MMP activity in atherosclerosis contributes to plaque instability. Some antimicrobial agents may attenuate MMP activity. Atherosclerotic lesions
Fábio Montico et al.
Anatomical record (Hoboken, N.J. : 2007), 296(11), 1758-1767 (2013-10-10)
The influence of senescence and hormone replacement on the onset of pathologic processes in the prostate is not yet fully understood. The aim was to identify the immunoreactivity and protein levels of molecules involved in cell proliferation, tissue remodeling and
Jonathan M Fahey et al.
The Journal of biological chemistry, 293(14), 5345-5359 (2018-02-15)
Endogenous nitric oxide (NO) generated by inducible NO synthase (iNOS) promotes glioblastoma cell proliferation and invasion and also plays a key role in glioblastoma resistance to chemotherapy and radiotherapy. Non-ionizing photodynamic therapy (PDT) has anti-tumor advantages over conventional glioblastoma therapies.

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