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Merck
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Documentos Principais

AB3542

Sigma-Aldrich

Anti-Monocarboxylate Transporter 2 Antibody

serum, Chemicon®

Sinônimo(s):

MCT2

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Preço e disponibilidade não estão disponíveis no momento.

fonte biológica

rabbit

Nível de qualidade

forma do anticorpo

serum

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

reatividade de espécies

rat

fabricante/nome comercial

Chemicon®

técnica(s)

ELISA: suitable
western blot: suitable

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

dry ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... SLC16A7(9194)

Especificidade

Recognizes rat Monocarboxylate Transporter 2 (MCT2). The immunogen shows no significant sequence homology with other MCT.

The immunogen sequence is 93% conserved in mouse and 66% in hamster. Reactivity with other species has not been confirmed.

Imunogênio

A 15 amino acid peptide sequence near the C-terminus of rat MCT2 (Jackson et al. 1997; Dao et al. 1998; Koehler-Stec et al. 1998; Price et al. 1998; Halestrap & Price 1999).

Aplicação

Anti-Monocarboxylate Transporter 2 Antibody is an antibody against Monocarboxylate Transporter 2 for use in ELISA & WB.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
Western blot

ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide (Catalog number AG218) per well.

Optimal working dilutions must be determined by the end user.

Ligação

Replaces: AB3542P

forma física

Rabbit serum. Liquid.

Armazenamento e estabilidade

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1


Certificados de análise (COA)

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J S Gilbert et al.
Placenta, 33(2), 100-105 (2011-12-22)
While utero-placental insufficiency is associated with adverse outcomes for both mother and fetus, many of the maternal-fetal adaptations during pregnancy in models of fetal compromise remain unclear. The purpose of this study was to determine if chronically reduced uterine perfusion
E M England et al.
Journal of animal science, 95(8), 3552-3562 (2017-08-15)
Acute activation of AMP-activated protein kinase (AMPK) increases monocarboxylate transporter (MCT) expression in skeletal muscle. However, the impact of chronic activation of AMPK on MCT expression in skeletal muscle is unknown. To investigate, MCT1, MCT2, and MCT4 mRNA expression and
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eLife, 12 (2023-11-14)
Astrocyte-derived L-lactate was shown to confer beneficial effects on synaptic plasticity and cognitive functions. However, how astrocytic Gi signaling in the anterior cingulate cortex (ACC) modulates L-lactate levels and schema memory is not clear. Here, using chemogenetic approach and well-established
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The consumption of glucose in the brain peaks during late childhood; yet, whether and how glucose metabolism is differentially regulated in the brain during childhood compared to adulthood remains to be understood. In particular, it remains to be determined how

Questions

  1. What is the molecular weight (MW) for the Western blot application of the product?

    1 answer
    1. In Western blot applications, the apparent molecular weight is usually slightly above the 50 kDa marker. This information is supported by a study titled "Altered lactate metabolism in Huntington's disease is dependent on GLUT3 expression" published in CNS Neurosci Ther. 2018 Apr;24(4):343-352 (PMID: 29582588).

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