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AB1745

Sigma-Aldrich

Anti-Connexin 45 Antibody, near CT, cytoplasmic

Chemicon®, from rabbit

Sinônimo(s):

Cx45

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

100

forma do anticorpo

purified antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

reatividade de espécies

rat, human, mouse

reatividade da espécie (prevista por homologia)

dog (based on 100% sequence homology)

fabricante/nome comercial

Chemicon®

técnica(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

nº de adesão UniProt

P36383

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

dog ... Gjc1(490936)
human ... GJC1(10052)
mouse ... Gjc1(14615)
rat ... Gjc1(266706)

Especificidade

Recognizes Human, rat and mouse Connexin 45. Due to sequence homologies, this antibody is also expected to react with canine (100% homology) Connexin 45. Other species not tested.

Imunogênio

KLH-conjugated synthetic, linear peptide corresponding to human Connexin 45 near the C-terminus.

Aplicação

Detect Connexin 45 using this Anti-Connexin 45 Antibody, near C-terminus, cytoplasmic validated for use in IP, WB, IH.

forma física

Format: Purified

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

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M Nitta et al.
Journal of animal science, 88(10), 3269-3279 (2010-06-22)
During mammalian oogenesis, intercellular communication between oocytes and the surrounding follicle cells through gap junction channels is crucial for oocyte development and maturation. The channel properties of gap junctions may be affected by the composition or combination of connexins, the
Erika R Kinjo et al.
PloS one, 9(10), e109149-e109149 (2014-10-10)
Gap junction (GJ) channels have been recognized as an important mechanism for synchronizing neuronal networks. Herein, we investigated the participation of GJ channels in the pilocarpine-induced status epilepticus (SE) by analyzing electrophysiological activity following the blockade of connexins (Cx)-mediated communication.
Loïc Le Gal et al.
Journal of the American Heart Association, 8(8), e010823-e010823 (2019-04-05)
Background Gap junction channels made of Connexin37 (Cx37) are expressed by aortic endothelial and smooth muscle cells of hypertensive mice, as well as by the renin-secreting cells of kidneys. Methods and Results To decipher whether Cx37 has any role in
Karen Maass et al.
Circulation research, 101(12), 1283-1291 (2007-10-13)
Haplodeficient mice expressing carboxyl-terminally truncated Cx43 (K258stop/KO), instead of the wild-type Cx43 isoform, reach adulthood and reveal no abnormalities in heart morphology. Here, we have analyzed the expression of K258stop protein and the morphology of gap junctions in adult hearts
Hanna Langhorst et al.
Disease models & mechanisms, 11(2) (2018-01-24)
CAR-like membrane protein (CLMP), an immunoglobulin cell adhesion molecule (IgCAM), has been implicated in congenital short-bowel syndrome in humans, a condition with high mortality for which there is currently no cure. We therefore studied the function of CLMP in a
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