8.52246

Fmoc-D-Tyr(PO(OBzl)OH)-OH

Novabiochem^®

• Sinônimo(s): Fmoc-D-Tyr(PO(OBzl)OH)-OH, N-α-Fmoc-O-benzyl-D-phosphotyrosine
• Fórmula empírica (Notação de Hill): C₃₁H₂₈NO₈P
• Peso molecular: 573.53
• Código UNSPSC: 12352209

Propriedades

• Nível de qualidade: 200
• linha de produto: Novabiochem^®
• Ensaio: ≥87.0% (acidimetric); ≥90.0% (HPLC); ≥95% (TLC)
• forma: powder
• adequação da reação: reaction type: Fmoc solid-phase peptide synthesis
• fabricante/nome comercial: Novabiochem^®
• aplicação(ões): peptide synthesis
• grupo funcional: Fmoc
• temperatura de armazenamento: 15-25°C

Descrição

Descrição geral

An excellent building block for the preparation of D-phosphotyrosine-containing peptides by Fmoc SPPS. This derivative can be introduced using standard activation methods, such as PyBOP^® and TBTU. The monoprotected phosphoserine residue once incorporated is stable to piperidine. Using this reagent, even peptides containing multiple phosphorylation sites can be prepared efficiently by standard Fmoc SPPS methods.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Fmoc SPPS of Peptides containing Post-Translational Modifications

Ligação

Replaces: 04-13-1080

Nota de análise

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): +14.0 - +18.0 °
Purity (TLC(CMA1)): ≥ 95 %
Assay (HPLC, area%): ≥ 90.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 87.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.3 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Informações legais

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable