8.08610

2,2,2-Trichloroethanol

for synthesis

• Sinônimo(s): 2,2,2-Trichloroethanol, ß,ß,ß-Trichloroethyl alcohol
• Fórmula empírica (Notação de Hill): C₂H₃Cl₃O
• Número CAS: 115-20-8
• Peso molecular: 149.40
• Número MDL: MFCD00004677
• Código UNSPSC: 12352104
• Número do índice EC: 204-071-0
• NACRES: NA.22
• Ensaio: ≥97.0% (GC)
• p.e.: 151-153 °C/1013 hPa
• pressão de vapor: 1.3 hPa ( 20 °C)

Propriedades

• pressão de vapor: 1.3 hPa ( 20 °C)
• Nível de qualidade: 200
• Ensaio: ≥97.0% (GC)
• Formulário: liquid
• temperatura de autoignição: 151 °C
• potência: 600 mg/kg LD₅₀, oral (Rat)
• pH: 5-6 (20 °C in H₂O, saturated solution)
• p.e.: 151-153 °C/1013 hPa
• pf: 17-18 °C
• temperatura de transição: flash point >110 °C
• densidade: 1.56 g/cm³ at 20 °C
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: ClC(Cl)(Cl)CO
• InChI: 1S/C2H3Cl3O/c3-2(4,5)1-6/h6H,1H2
• chave InChI: KPWDGTGXUYRARH-UHFFFAOYSA-N

Descrição

Aplicação

• Assessment of EDDP Perchlorate Stability in Biological Samples: An investigation focused on the stability of methaDoneand its main metabolite, EDDP perchlorate, in oral fluids. The study highlighted the importance of understanding metabolite stability for accurate drug testing and monitoring in forensic and clinical settings (Fucci and De Giovanni, 2008).



• EDDP Perchlorate in Drug Testing: EDDP perchlorate was examined in a forensic context using the SPME technique to simultaneously detect multiple drugs of abuse in saliva. This method underscores the utility of EDDP perchlorate as a reliable biomarker in toxicology studies and drug monitoring (Fucci, De Giovanni, and Chiarotti, 2003).



• Pharmacological Action of MethaDoneand Metabolites: Research explored the interaction of methaDoneand its metabolites, including EDDP perchlorate, with rat alpha3beta4 nicotinic receptors. These findings contribute to the understanding of the pharmacodynamic properties of methadone′s metabolites, relevant in the development of therapeutic and diagnostic strategies (Xiao et al., 2001).

Nota de análise

Assay (GC, area%): ≥ 97.0 % (a/a)
Density (d 20 °C/ 4 °C): 1.551 - 1.561
Identity (IR): passes test
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

Informações de segurança

• Pictogramas: GHS05,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H302 - H318 - H336
• Declarações de precaução: P261 - P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
• Órgãos-alvo: Central nervous system
• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 230.0 °F - closed cup
• Ponto de fulgor (°C): 110 °C - closed cup