609312

Thyroglobulin, Human Thyroid

• Sinônimo(s): Thyroglobulin, Human Thyroid
• Número CAS: 9010-34-8
• Código UNSPSC: 12352202
• NACRES: NA.25

Propriedades

• fonte biológica: human thyroid
• Nível de qualidade: 100
• Ensaio: ≥95% (PAGE)
• forma: lyophilized
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze
• Condições de expedição: wet ice
• temperatura de armazenamento: 2-8°C

Descrição

Descrição geral

Native thyroglobulin, consisting of two polypeptide monomers of 33 kDa each, purified from human thyroid. This protein is an excellent source of N-linked glycans of various structures, including sialylated core fucose and oligomannose oligosaccharides. Also, Gal-3-SO₄ and GalNAc-6-SO₄ residues located in a single multi-branched complex type glycan have been reported in calf thymus and human proteins.

Native thyroglobulin, consisting of two polypeptide monomers of 330 kDa each, purified from human thyroid. This protein is an excellent source of N-linked glycans of various structures, including sialylated core fucose and oligomannose oligosaccharides. Also, Gal-3-SO₄ and GalNAc-6-SO₄ residues located in a single multi-branched complex type glycan have been reported in calf thymus and human proteins. When subjected to native PAGE this protein shows a band at

~660 kDa, representing the dimeric form, and another band at ~330 kDa, representing the monomeric form.

Advertência

Toxicity: Standard Handling (A)

forma física

Lyophilized from 20 mM NH₄HCO₃.

Nota de preparo

Prepared from tissues of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstituição

Reconstitute in phosphate buffer, containing 150 mM NaCl, pH >7.0.

Outras notas

Rawitch, A.B., et al. 1993. Arch. Biochem. Biophys. 300, 271.
Black, E.G., and Sheppard, M.C. 1991. Clin. Endocrinol. 35, 519.
Spiro, R.G., and Bhoyroo, V.D. 1988. J. Biol. Chem. 263, 14351.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3