524736

Phosphodiesterase 4B2, His•Tag^®, Human, Recombinant, S. frugiperda

• Sinônimo(s): PDE4B2, cAMP-Specific Phosphodiesterase 4B2
• Código UNSPSC: 12352202
• NACRES: NA.54

Propriedades

• recombinante: expressed in baculovirus infected Spodoptera frugiperda cells
• Nível de qualidade: 100
• forma: liquid
• atividade específica: ≥0.25 U/μL
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze; avoid repeated freeze/thaw cycles
• Condições de expedição: wet ice
• temperatura de armazenamento: −70°C

Descrição

Descrição geral

Full-length, recombinant, human phosphodiesterase 4B2 (accession no. L20971) fused at the N-terminus to a His•Tag sequence and expressed in S. frugiperda using a baculovirus expression system. Plays a significant role in the regulation of inflammatory cell activation. PDE4B2 is a predominant isoform in neutrophils and monocytes. Supplied as a partially purified, catalytically active preparation.

Advertência

Toxicity: Standard Handling (A)

Definição da unidade

One unit is defined as the amount of enzyme that will convert 1 pmol cAMP to AMP per min at 30°C, pH 7.5.

forma física

In 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3.

Reconstituição

Following initial thaw, aliquot and freeze (-70°C).

Outras notas

Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol.538, 39.
Smith, P.G., et al. 2005 Blood105, 308.
Baroja, M.L., et al. 1999. J. Immunol.162, 2016.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable