5.08052

iMDK

≥98% (HPLC), solid, midkine inhibitor, Calbiochem^®

• Sinônimo(s): Midkine Inhibitor, iMDK, 3-(2-(4-Fluorobenzyl)imidazo[2,1-b]thiazol-6-yl)-2H-chromen-2-one, 3-(2-(4-Fluorobenzyl)imidazo[2,1-b][1,3]thiazol-6-yl)-2H-chromen-2-one, MDK Expression Inhibitor
• Fórmula empírica (Notação de Hill): C₂₁H₁₃FN₂O₂S
• Número CAS: 881970-80-5
• Peso molecular: 376.40
• Código UNSPSC: 12352200
• ID de substância PubChem: 15991416
• NACRES: NA.77

Propriedades

• product name: Midkine Inhibitor, iMDK,
• Ensaio: ≥98% (HPLC)
• Nível de qualidade: 100
• forma: solid
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze; protect from light
• cor: off-white
• solubilidade: DMSO: 5 mg/mL
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: C1=CC=C2C(=C1)C=C(C(=O)O2)C3=CN4C=C(SC4=N3)CC5=CC=C(C=C5)F

Descrição

Descrição geral

The midkine inhibitor, iMDK, demonstrates strong antiproliferative and antitumor effects both in vitro and in vivo in non-small-cell lung cancer. It also induces apoptosis of primary effusion lymphoma through G2/M cell cycle arrest.

Aplicação

Midkine Inhibitor, iMDK may be used to study its anti-cancer activity on primary effusion lymphoma (PEL) in vitro.

Ações bioquímicas/fisiológicas

Cell permeable: yes

Primary Target
Midkine

Reversible: yes

Embalagem

Packaged under inert gas

Advertência

Toxicity: Standard Handling (A)

Reconstituição

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Outras notas

Hao, H., et al. 2013. PLoS ONE8, e71093.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable