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Documentos Principais

217503

Sigma-Aldrich

Cardiotoxin

from Naja pallida, ≥95% (HPLC), lyophilized solid, cytolytic toxin, Calbiochem®

Sinônimo(s):

Cardiotoxin, Naja pallida

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About This Item

Número CAS:
Número MDL:
Código UNSPSC:
12352202
NACRES:
NA.32
Preço e disponibilidade não estão disponíveis no momento.

Nome do produto

Cardiotoxin, Naja pallida,

descrição

Merck USA index - 14, 1835

Nível de qualidade

Ensaio

≥95% (HPLC)

Formulário

lyophilized solid

fabricante/nome comercial

Calbiochem®

condição de armazenamento

OK to freeze

solubilidade

water: 1 mg/mL

Condições de expedição

ambient

temperatura de armazenamento

2-8°C

Descrição geral

Cardiotoxins, which are highly basic peptides, interact with negatively charged lipids on membranes. While the presence of Lysine residues is crucial for their activity, cardiotoxins demonstrate varying effects on different cells, indicating selective binding to certain cell types.[1]

Aplicação

Cardiotoxin, Naja pallida has been used:
  • to inject into the TA of the 4-month-old dystrophic mice to address whether ILA treatment could modulate muscle regeneration[2]
  • to induce a skeletal muscle injury into the right TA muscle[3]
  • to induce muscle regeneration[4]

Advertência

Toxicity: Harmful (C)

Reconstituição

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Outras notas

Jang, J.Y., et al. 1997. Biochemistry 36, 4635.
Huang, J.L., and Trumble, W.R. 1991. Toxicon29, 31.
Raynor, R.L., et al. 1991. J. Biol. Chem.266, 2753.
Grognet, J.M., et al. 1986. Mol. Immunol.23, 132.

Informações legais

Not available for sale outside of the United States.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Cell Death & Disease, 15(3), 201-201 (2024)
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Harvey, Alan L
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Evaluation of pro-regenerative and anti-inflammatory effects of isolecanoric acid in the muscle: Potential treatment of Duchenne Muscular Dystrophy
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How satellite cells and their progenitors balance differentiation and self-renewal to achieve sustainable tissue regeneration is not well understood. A major roadblock to understanding satellite cell fate decisions has been the difficulty of studying this process in vivo. By visualizing expression

Questions

  1. Re 217503 Cardiotoxin, Naja pallida - could you please ask your supplier for more details on this protein: which form of 3FTx is it ? Can they give me an accession number or a UniProt entry, thanks.

    1 answer
    1. This product is classified as Cytotoxin 1. The UniProt accession number is P01468. Please see the link below to review the UniProt profile:
      https://www.uniprot.org/uniprotkb/P01468/entry

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