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Merck
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Documentos

07-318

Sigma-Aldrich

Anti-TBX2 Antibody

serum, Upstate®

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

forma do anticorpo

serum

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

reatividade de espécies

mouse, human

fabricante/nome comercial

Upstate®

técnica(s)

immunoprecipitation (IP): suitable
western blot: suitable

Isotipo

IgG

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

dry ice

Informações sobre genes

human ... TBX2(6909)

Especificidade

TBX2

Imunogênio

GST fusion protein corresponding to residues 554-702 of human TBX2

Aplicação

Detect TBX2 also known as T-box 2 with Anti-TBX2 Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in IP & WB.

Qualidade

routinely evaluated by immunoblot on RIPA lysates from MCF-7 human breast adenocarcinoma cells

Descrição-alvo

74kDa

forma física

antiserum with 0.05% sodium azide before the addition of glycerol to 30%

Informações legais

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Juan Aparicio-Blanco et al.
Drug delivery and translational research (2024-05-13)
Brain drug delivery is severely hindered by the presence of the blood-brain barrier (BBB). Its functionality relies on the interactions of the brain endothelial cells with additional cellular constituents, including pericytes, astrocytes, neurons, or microglia. To boost brain drug delivery
J J Jacobs et al.
Nature genetics, 26(3), 291-299 (2000-11-04)
To identify new immortalizing genes with potential roles in tumorigenesis, we performed a genetic screen aimed to bypass the rapid and tight senescence arrest of primary fibroblasts deficient for the oncogene Bmi1. We identified the T-box member TBX2 as a
Timo H Lüdtke et al.
Respiratory research, 22(1), 85-85 (2021-03-19)
Tbx2 encodes a transcriptional repressor implicated in the development of numerous organs in mouse. During lung development TBX2 maintains the proliferation of mesenchymal progenitors, and hence, epithelial proliferation and branching morphogenesis. The pro-proliferative function was traced to direct repression of
Chen-Leng Cai et al.
Development (Cambridge, England), 132(10), 2475-2487 (2005-04-22)
Mutations in T-box genes are the cause of several congenital diseases and are implicated in cancer. Tbx20-null mice exhibit severely hypoplastic hearts and express Tbx2, which is normally restricted to outflow tract and atrioventricular canal, throughout the heart. Tbx20 mutant
K L Redmond et al.
Oncogene, 29(22), 3252-3262 (2010-03-30)
T-box 2 (TBX2) is a transcription factor involved in mammary development and is known to be overexpressed in a subset of aggressive breast cancers. TBX2 has previously been shown to repress growth control genes such as p14(ARF) and p21(WAF1/cip1). In

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