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T-904

Supelco

Trimipramine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (Notação de Hill):
C20H26N2
Número CAS:
739-71-9
Peso molecular:
294.43
Número MDL:
MFCD00242595
Código UNSPSC:
41116107
ID de substância PubChem:
329826892
NACRES:
NA.24

grau

certified reference material

forma

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

embalagem

ampule of 1 mL

fabricante/nome comercial

Cerilliant®

concentração

1.0 mg/mL in methanol

técnica(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicação(ões)

clinical testing

formato

single component solution

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CN(C)CC(C)CN1C2=C(C=CC=C2)CCC3=C1C=CC=C3

InChI

1S/C20H26N2/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22/h4-11,16H,12-15H2,1-3H3

chave InChI

ZSCDBOWYZJWBIY-UHFFFAOYSA-N

Informações sobre genes

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , DRD2(1813) , HRH1(3269) , HTR2A(3356) , HTR2C(3358) , SLC6A2(6530)

Descrição geral

Trimipramine is a tricyclic antidepressant prescribed for treatment of depression, insomnia, and chronic pain or as an adjunctive therapy for alcohol or opioid withdrawal. This certified solution standard is applicable for use in clinical toxicology, forensic analysis, or urine drug testing applications by LC-MS/MS or GC/MS. Trimipramine is marketed under the trade names Surmontil®, Rhotrimine, and Stangyl.

Informações legais

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Surmontil is a registered trademark of Pliva, Inc.

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órgãos-alvo

Eyes,Central nervous system

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

49.5 °F - closed cup

Ponto de fulgor (°C)

9.7 °C - closed cup

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Donald F Smith et al.
Psychopharmacology, 195(1), 131-138 (2007-07-27)
Molecular tools are needed for assessing anti-depressant actions by positron emission tomography (PET) in the living human brain. This study determined whether [(11)C]mirtazapine is an appropriate molecular tool for use with PET to estimate the magnitude of neuroreceptor occupancy produced
Britta Haenisch et al.
Psychopharmacology, 217(2), 289-295 (2011-04-13)
The antidepressant trimipramine shows an atypical pharmacological profile and its mechanism of action is still obscure. The present study investigated whether trimipramine and three of its metabolites interact with targets of other antidepressants, namely, the human monoamine transporters for noradrenaline
Yusuf Oztürk et al.
Pharmacology, biochemistry, and behavior, 83(4), 592-597 (2006-05-23)
The present study was designed to investigate the involvement of endogenous opioid systems in the antinociception induced by the antidepressant drugs, desipramine and trimipramine. For this purpose, the antinociceptive effects of desipramine (7.5 and 15.0 mg/kg i.p.) and trimipramine (5.0
Ali R Fakhari et al.
Electrophoresis, 33(3), 506-515 (2012-01-31)
A sensitive, simple and reproducible method was developed for preconcentration and determination of trimipramine (TPM) enantiomers in biological samples using electromembrane extraction combined with cyclodextrin-modified capillary electrophoresis (CE). During the extraction, TPM enantiomers migrated from a 5 mL sample solution through
Diansong Zhou et al.
Drug metabolism and disposition: the biological fate of chemicals, 38(5), 863-870 (2010-02-06)
The role of human UDP glucuronosyltransferase (UGT) 2B10 in the N-glucuronidation of a number of tricyclic antidepressants was investigated and compared with that of UGT1A4 in both the Sf9 expressed system and human liver microsomes. The apparent K(m) (S(50)) values
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