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880230C

Avanti

18:1 PEG5000 PE

Avanti Research™ - A Croda Brand 880230C

Sinônimo(s):

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] (ammonium salt)

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25 MG
R$ 750,00

R$ 750,00

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25 MG
R$ 750,00

About This Item

Número CAS:
474922-90-2
Número MDL:
MFCD02262251
Código UNSPSC:
12352211
NACRES:
NA.25

R$ 750,00

Check Cart for Availability
Solicite uma grande encomenda

Formulário

liquid

embalagem

pkg of 1 × 2.5 mL (880230C-25mg)
pkg of 2 × 4 mL (880230C-200mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand 880230C

concentração

10 mg/mL (880230C-25mg)
25 mg/mL (880230C-200mg)

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[H][C@@](COP([O-])(OCCNC([(OCH2CH2)113OCH3])=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

Aplicação

18:1 PEG5000 PE or 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 has been used in small unilamellar vesicles (SUV)[1].

Ações bioquímicas/fisiológicas

18:1 PEG5000 PE, also known as 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000], is used along with lipid modified dendrimer copolymer to co-deliver siRNA and drugs to tumors.[2]

Embalagem

5 mL Clear Glass Sealed Ampule (880230C-200mg)
5 mL Clear Glass Sealed Ampule (880230C-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Órgãos-alvo

Liver,Kidney, Respiratory system

Código de classe de armazenamento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

does not flash

Ponto de fulgor (°C)

does not flash

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Certificados de análise (COA)

Lot/Batch Number

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TCR--pMHC bond conformation controls TCR ligand discrimination
Sasmal DK, et al.
Cellular & Molecular Immunology, 65-76 (2017)
Xiaolei Su et al.
Methods in molecular biology (Clifton, N.J.), 1584, 65-76 (2017-03-04)
Biochemical reconstitution has served as an important tool for understanding the mechanisms of many cellular processes including DNA replication, transcription, translation, vesicle trafficking, and ubiquitin-mediated proteolysis. Here, we demonstrate that biochemical reconstitution can be applied to studying a complex signaling
Reconstitution of TCR signaling using supported lipid bilayers
Su X, et al.
Methods in Molecular Biology (2017)
Dibyendu K Sasmal et al.
Cellular & molecular immunology, 17(3), 203-217 (2019-09-19)
A major unanswered question is how a TCR discriminates between foreign and self-peptides presented on the APC surface. Here, we used in situ fluorescence resonance energy transfer (FRET) to measure the distances of single TCR-pMHC bonds and the conformations of
Jiayi Pan et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 136, 18-28 (2019-01-12)
Multidrug resistance (MDR) significantly decreases the therapeutic efficiency of anti-cancer drugs. Its reversal could serve as a potential method to restore the chemotherapeutic efficiency. Downregulation of MDR-related proteins with a small interfering RNA (siRNA) is a promising way to reverse
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