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Documentos Principais

790404P

Avanti

18:1 DGS-NTA(Ni)

Avanti Research - A Croda Brand

Sinônimo(s):

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (nickel salt); DOGS NTA

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About This Item

Fórmula empírica (Notação de Hill):
C53H93N2O15Ni
Número CAS:
Peso molecular:
1057.00
Número MDL:
Código UNSPSC:
12352211
NACRES:
NA.25
Preço e disponibilidade não estão disponíveis no momento.

descrição

1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (nickel salt)

Ensaio

>99% (TLC)

Formulário

powder

embalagem

pkg of 1 × 10 mg (790404P-10mg)
pkg of 1 × 25 mg (790404P-25mg)
pkg of 1 × 5 mg (790404P-5mg)

fabricante/nome comercial

Avanti Research - A Croda Brand

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

Descrição geral

1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] nitrilotriacetic acid (NTA) (18:1 DGS-NTA(Ni)) is a conjugated phospholipid[1] that contains nickel.[2] NTA chelates with four of the six coordination sites present in nickel ion.[3]

Aplicação

1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (nickel salt) (18:1 DGS-NTA(Ni)) has been used:
  • in the preparation of liposomes with porphyrin-phospholipid (PoP) conjugate for protein and peptide binding studies[1]
  • in the preparation of nanosize multillamelar vesicles (NMVs) for antigen delivery studies[2]
  • as a component of small unilamellar vesicle (SUV) for planar lipid membrane (PM) preparation[4]

Ações bioquímicas/fisiológicas

1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] nitrilotriacetic acid (NTA) (18:1 DGS-NTA(Ni)) is useful in structural biology especially to bind recombinant histidine tagged proteins.[1] Though useful, being nanoparticulate it has stability problems in biological samples. So NTA-lipid conjugate is majorly used as liposomes or as a coating to nanoparticle.[1] DGS-NTA (Ni) based nanosize multillamelar vesicles (NMVs) are potent vaccine delivery system.[2]

Embalagem

5 mL Clear Glass Sealed Ampule (790404P-10mg)
5 mL Clear Glass Sealed Ampule (790404P-25mg)
5 mL Clear Glass Sealed Ampule (790404P-5mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

geralmente comprado junto com este produto

Código de classe de armazenamento

11 - Combustible Solids


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