870865P

BMP22

Avanti Research^™ - A Croda Brand, powder

• Sinônimo(s): 4-pentadecylbenzylphosphonic acid
• Fórmula empírica (Notação de Hill): C₂₂H₃₉O₃P
• Número CAS: 1306684-90-1
• Peso molecular: 382.52
• Código UNSPSC: 12352211
• NACRES: NA.25

Propriedades

• Ensaio: 99% (TLC)
• forma: powder
• embalagem: pkg of 1 × 1 mg (870865P-1mg); pkg of 1 × 5 mg (870865P-5mg)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand
• tipo de lipídio: bioactive lipids
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: CCCCCCCCCCCCCCCC1=CC=C(CP(O)(O)=O)C=C1

Descrição

Descrição geral

BMP (bis(monoacylglycerol)phosphate) is synthesized from phosphatidylglycerol (PG) in alveolar macrophages. BMP is a unique phospholipid having a glycerol phosphate ester at sn-1 position rather than sn-3 and has one acyl group attached to each of the glycerol moieties. The acyl groups of BMP is rich in polyunsaturated species.

Ações bioquímicas/fisiológicas

BMP (bis(monoacylglycerol)phosphate) (BMP) is found in the retinal pigment epithelium of healthy human retina. BMP lipids regulates cholesterol level in endosomes. It is implicated in endosomal/lysosomal storage diseases like Niemann-Pick and neuronal ceroid lipofuscinosis diseases. BMP22/4PBPA is a small molecule inhibitor of autotaxin (ATX). 4PBPA has relatively a longer half-life and also reduces the lysophosphatidic acid concentration in plasma. BMP22 is implicated in reducing the bone erosion and systemic bone loss.

Embalagem

5ML Glass Amber Screw Cap Vial (870865P-1MG)

5ML Glass Amber Screw Cap Vial (870865P-5MG)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable