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850468C

Avanti

18:0-18:2 PC

1-stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine, chloroform

Sinônimo(s):

1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine; PC(18:0/18:2(9Z,12Z))

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About This Item

Fórmula empírica (Notação de Hill):
C44H84NO8P
Número CAS:
Peso molecular:
786.11
Código UNSPSC:
51191904
NACRES:
NA.25

Ensaio

>99% (TLC)

forma

liquid

embalagem

pkg of 1 × 2.5 mL (850468C-25mg)
pkg of 2 × 4 mL (850468C-200mg)

fabricante/nome comercial

Avanti Research - A Croda Brand 850468C

concentração

10 mg/mL (850468C-25mg)
25 mg/mL (850468C-200mg)

tipo de lipídio

phospholipids
cardiolipins

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O

InChI

1S/C44H84NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h15,17,21,23,42H,6-14,16,18-20,22,24-41H2,1-5H3/b17-15-,23-21-/t42-/m1/s1

chave InChI

FORFDCPQKJHEBF-VPUSDGANSA-N

Descrição geral

18:0-18:2 PC is a non-fragmented oxidized phosphotidylcholine. It is a component of low density lipoprotein (LDL), which is a polyunsaturated fatty acid.

Aplicação

18:0-18:2 PC may be used to study the effect of phospholipids on lubrication of damaged mesothelium of lungs. It has been used for the preparation of liposomes.

Embalagem

5 mL Clear Glass Sealed Ampule (850468C-200mg)
5 mL Clear Glass Sealed Ampule (850468C-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Órgãos-alvo

Liver,Kidney, Respiratory system

Código de classe de armazenamento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

does not flash

Ponto de fulgor (°C)

does not flash


Certificados de análise (COA)

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Differential ligand binding specificities of the pulmonary collectins are determined by the conformational freedom of a surface loop
Rynkiewicz M J, et al.
Biochemistry, 56(31), 4095-4105 (2017)
Lubricating recovery of damaged pleural mesothelium: effect of time and of phosphatidylcholines
Bodega F, et al.
Respiratory Physiology & Neurobiology, 203(2), 116-120 (2014)
Oxidized phosphatidylcholines are produced in renal ischemia reperfusion injury
Solati Z, et al.
PLoS ONE, 13(4), e0195172-e0195172 (2018)
Ginger L Milne et al.
Journal of lipid research, 46(2), 307-319 (2004-11-18)
Phospholipids reside in the surface layer of LDLs and constitute approximately 20-25% of the particle by weight. We report a study of the primary products generated from the most abundant molecular species of phosphatidylcholines present in LDL during in vitro
Wenbo Cao et al.
Analytical chemistry, 90(17), 10286-10292 (2018-08-11)
The presence of carbon-carbon double bonds (C═Cs) in unsaturated phospholipids is closely related to lipid conformations and physiochemical activities. Previously, we have demonstrated that epoxidation reaction facilitated by low-temperature plasma (LTP) enabled the structural analysis of unsaturated fatty acids (FAs).

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