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840435P

Avanti

12:0 PG

Avanti Research™ - A Croda Brand

Sinônimo(s):

1,2-didodecanoyl-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); DLPG; PG(12:0/12:0)

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R$ 467,00
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R$ 1.377,00

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R$ 467,00
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About This Item

Fórmula empírica (Notação de Hill):
C30H58O10PNa
Número CAS:
322647-27-8
Peso molecular:
632.74
Número MDL:
MFCD00135194
Código UNSPSC:
51191904
NACRES:
NA.25

R$ 467,00

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descrição

1,2-dilauroyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)

Ensaio

>99% (TLC)

Formulário

powder

embalagem

pkg of 1 × 200 mg (840435P-200mg)
pkg of 1 × 25 mg (840435P-25mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand

tipo de lipídio

cardiolipins
phospholipids

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCC)COC(=O)CCCCCCCCCCC)OCC(O)CO

InChI

1S/C30H59O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-29(33)37-25-28(26-39-41(35,36)38-24-27(32)23-31)40-30(34)22-20-18-16-14-12-10-8-6-4-2;/h27-28,31-32H,3-26H2,1-2H3,(H,35,36);/q;+1/p-1/t27?,28-;/m1./s1

chave InChI

CIRSYGHBBDDURM-AMRYRHMLSA-M

Descrição geral

Phosphatidylglycerol (PG) is one of the most important lipid, found in Gram-positive bacteria. It has odd-numbered branched-chain fatty acids as acyl chains.[1] This phospholipid is ubiquitously present in the membranes of several organisms.[2] 12:0 PG (1,2-dilauroyl-sn-glycero-3-phospho-(1′-rac-glycerol)/DLPG) is an anionic phospholipid. It is an anionic analogue of the zwitterionic phospholipid, dilauroyl phosphatidylcholine (DLPC).[3]

Aplicação

12:0 PG (1,2-dilauroyl-sn-glycero-3-phospho-(1′-rac-glycerol)) has been used in monomolecular films as representative lipid component of eukaryotic membranes to study the generality of the non-steroidal anti-inflammatory drug (NSAID)-related effect.[4] It may also be used:
  • in the preparation of liposomes for PagP folding assays[5]
  • as a component in pyrene labeleld liposomes[6]
  • to construct liposome/lipid vesicle[7]

Ações bioquímicas/fisiológicas

Phosphatidylglycerol (PG) is known to participate in photosynthesis.[2]

Embalagem

5 mL Amber Glass Screw Cap Vial (840435P-200mg)
5 mL Amber Glass Screw Cap Vial (840435P-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

geralmente comprado junto com este produto

Nº do produto
Descrição
Preços

Código de classe de armazenamento

11 - Combustible Solids

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Lindsay M McMorran et al.
Journal of molecular biology, 425(17), 3178-3191 (2013-06-26)
Although many periplasmic folding factors have been identified, the mechanisms by which they interact with unfolded outer membrane proteins (OMPs) to promote correct folding and membrane insertion remain poorly understood. Here, we have investigated the effect of two chaperones, Skp
Lloyd Ryan et al.
The Journal of biological chemistry, 288(28), 20162-20172 (2013-06-06)
Antimicrobial or host defense peptides are innate immune regulators found in all multicellular organisms. Many of them fold into membrane-bound α-helices and function by causing cell wall disruption in microorganisms. Herein we probe the possibility and functional implications of antimicrobial
FATS vert Occurrence
Encyclopedia of food sciences and nutrition, 2293-2296 (2003)
Gerardino D'Errico et al.
Biochimica et biophysica acta, 1778(12), 2710-2716 (2008-08-19)
There is mounting evidence that the lipid matrix of neuronal cell membranes plays an important role in the accumulation of beta-amyloid peptides into senile plaques, one of the hallmarks of Alzheimer's disease (AD). With the aim to clarify the molecular
Brianna M Abbott et al.
Biochimica et biophysica acta. Biomembranes, 1860(5), 1187-1192 (2018-02-13)
Experiments investigating the adsorption and desorption of cytochrome c onto and from liposomes containing 50 mol% 1,2-diacylphosphatidylglycerol lipids [10:0, 12:0, 14:0, 16:0, 18:1(Δ9 cis)] with 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine (DOPC) in pH 7.4 buffered solutions of low to moderate ionic strength are reported. Fluorescence experiments
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Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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