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810133C

Avanti

18:1-12:0 NBD PC

Avanti Research™ - A Croda Brand 810133C

Sinônimo(s):

1-Oleoyl-2-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sn-Glycero-3-Phosphocholine

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About This Item

Fórmula empírica (Notação de Hill):
C44H76N5O11P
Número CAS:
190792-36-0
Peso molecular:
882.07
Código UNSPSC:
12352211
NACRES:
NA.25

Ensaio

>99% (TLC)

forma

liquid

embalagem

pkg of 1 × 1 mL (810133C-1mg)
pkg of 5 × 1 mL (810133C-5mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand 810133C

concentração

1 mg/mL (810133C-1mg)
1 mg/mL (810133C-5mg)

tipo de lipídio

fluorescent lipids
phospholipids

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

Descrição geral

Phosphatidylcholine (PC) is a prime metabolite in eukaryotes glycerolipid metabolism, mainly synthesized in liver. It is a major element of lipoproteins, bile and lung surfactant. NBD PC contains 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) covalently attached to phosphatidylcholine.

Aplicação

18:1-06:0 NBD PC is suitable for:
  • the generation giant unilamellar vesicles (GUVs) subjected to fluorescence microscopy
  • labelling lipid bilayers formed by vesicle fusion in order to study the lipid distribution by fluorescence microscopy
  • the preparation of phospholipid-coated beads

Ações bioquímicas/fisiológicas

7-nitrobenz-2-oxa-1,3-diazol-4-yl phosphatidylcholine (NBD PC) functions as a fluorescent analog in biological membranes in order to study the cellular processes.

Embalagem

5 mL Amber Glass Screw Cap Vial (810133C-1mg)
5 mL Amber Glass Screw Cap Vial (810133C-5mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Órgãos-alvo

Central nervous system, Liver,Kidney

Classe de risco de água (WGK)

WGK 3

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Laura K Cole et al.
Biochimica et biophysica acta, 1821(5), 754-761 (2011-10-08)
Phosphatidylcholine (PC) is the major phospholipid component of all plasma lipoprotein classes. PC is the only phospholipid which is currently known to be required for lipoprotein assembly and secretion. Impaired hepatic PC biosynthesis significantly reduces the levels of circulating very
Wan-Chen Lin et al.
Biophysical journal, 90(1), 228-237 (2005-10-11)
A fundamental attribute of cell membranes is transmembrane asymmetry, specifically the formation of ordered phase domains in one leaflet that are compositionally different from the opposing leaflet of the bilayer. Using model membrane systems, many previous studies have demonstrated the
Henry A Boumann et al.
Biochimica et biophysica acta, 1788(7), 1444-1451 (2009-04-21)
Anammox bacteria that are capable of anaerobically oxidizing ammonium (anammox) with nitrite to nitrogen gas produce unique membrane phospholipids that comprise hydrocarbon chains with three or five linearly condensed cyclobutane rings. To gain insight into the biophysical properties of these
Sang-Yeob Kim et al.
PloS one, 12(4), e0174603-e0174603 (2017-04-05)
The removal of unwanted or damaged cells by phagocytes is achieved via a finely regulated cleaning process called efferocytosis. To characterize the mechanisms through which phagocytes control the intake of apoptotic cells, we investigated how the phagocyte's appetite for engulfed
Haijia Yu et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(16), 4362-4367 (2016-04-05)
Organelles are in constant communication with each other through exchange of proteins (mediated by trafficking vesicles) and lipids [mediated by both trafficking vesicles and lipid transfer proteins (LTPs)]. It has long been known that vesicle trafficking can be tightly regulated
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