H54409

trans-4-Hydroxy-L-proline

≥99%, for peptide synthesis

• Sinônimo(s): (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, Hyp
• Fórmula empírica (Notação de Hill): C₅H₉NO₃
• Número CAS: 51-35-4
• Peso molecular: 131.13
• Beilstein: 81441
• Número CE: 200-091-9
• Número MDL: MFCD00064320
• Código UNSPSC: 12352209
• ID de substância PubChem: 24895692
• NACRES: NA.22

Propriedades

• product name: trans-4-Hydroxy-L-proline, ≥99%
• Ensaio: ≥99%
• forma: crystalline powder
• atividade óptica: [α]25/D −75.6°, c = 1 in H₂O
• adequação da reação: reaction type: solution phase peptide synthesis
• cor: white to off-white
• pf: 273 °C (dec.) (lit.)
• aplicação(ões): peptide synthesis
• cadeia de caracteres SMILES: O[C@H]1CN[C@@H](C1)C(O)=O
• InChI: 1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1
• chave InChI: PMMYEEVYMWASQN-DMTCNVIQSA-N

Descrição

Descrição geral

Trans-4-hydroxy-L-proline is an isomer of hydroxyproline used as a chiral building block in the production of many pharmaceuticals like neuroexcitatory kainoids.

Aplicação

Versatile reagent for the synthesis of neuroexcitatory kainoids and antifungal echinocandins. Also employed in the synthesis of chiral ligands for enantioselective ethylation of aldehydes.

Outras notas

Natural constituent of animal structural proteins such as collagen and elastin.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)