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A10809

Sigma-Aldrich

4′-Hydroxy-3′-methoxyacetophenone

98%

Sinônimo(s):

Acetovanillone, Apocynin

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About This Item

Fórmula linear:
HOC6H3(OCH3)COCH3
Número CAS:
498-02-2
Peso molecular:
166.17
Beilstein:
637373
Número CE:
207-854-5
Número MDL:
MFCD00008747
Código UNSPSC:
12352100
ID de substância PubChem:
24890503
NACRES:
NA.22
Preço e disponibilidade não estão disponíveis no momento.

Ensaio

98%

Formulário

powder

p.e.

263-265 °C/17 mmHg (lit.)

pf

112-115 °C (lit.)

cadeia de caracteres SMILES

COc1cc(ccc1O)C(C)=O

InChI

1S/C9H10O3/c1-6(10)7-3-4-8(11)9(5-7)12-2/h3-5,11H,1-2H3

chave InChI

DFYRUELUNQRZTB-UHFFFAOYSA-N

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Categorias relacionadas

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319,H335

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análise (COA)

Lot/Batch Number
SDBB1075
STBL0772
STBK6806
STBK5573
STBK1089

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Elham Khanicheh et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(9), 2187-2192 (2013-08-03)
Antioxidative drugs continue to be developed for the treatment of atherosclerosis. Apocynin is an nicotinamide adenine dinucleotide phosphate oxidase inhibitor with anti-inflammatory properties. We used contrast-enhanced ultrasound molecular imaging to assess whether short-term apocynin therapy in atherosclerosis reduces vascular oxidative
Jingfei Zhang et al.
Neuron, 82(1), 195-207 (2014-03-19)
Complement receptor 3 (CR3) activation in microglia is involved in neuroinflammation-related brain disorders and pruning of neuronal synapses. Hypoxia, often observed together with neuroinflammation in brain trauma, stroke, and neurodegenerative diseases, is thought to exacerbate inflammatory responses and synergistically enhance brain
Ji Chen et al.
Hypertension (Dallas, Tex. : 1979), 61(3), 681-689 (2012-12-26)
Angiotensin-converting enzyme 2 (ACE2) is a lately discovered enzyme catalyzing Angiotensin II into Angiotensin 1-7. Angiotensin II has been reported to impair endothelial progenitor cell (EPC) function and is detrimental to stroke. Here, we studied the role of ACE2 in
Stephen J Kentish et al.
The Journal of physiology, 592(15), 3287-3301 (2014-06-01)
Neuronal nitric oxide (NO) plays an important role in gastric motor activity and modulates the mechanosensitivity of gastro-oesophageal vagal afferents. Effects of NO on food intake are dependent on feeding status. We sought to determine the effect of NO on
Julio Madrigal-Matute et al.
Journal of the American Heart Association, 3(4) (2014-08-07)
Galectin-3 (Gal-3) participates in different mechanisms involved in atherothrombosis, such as inflammation, proliferation, or macrophage chemotaxis. Thus, there have been committed intensive efforts to elucidate the function of Gal-3 in cardiovascular (CV) diseases. The role of Gal-3 as a circulating
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Questions

1–5 of 5 Questions  

  1. I'm looking for apocynin. Is A10809 the right product?

    1 answer

    1. Yes, apocynin is a common synonym for 4´-hydroxy-3´-methoxyacetophenone.

      Helpful?

  2. Can I use Product A10809, Apocynin, in cell culture?

    1 answer

    1. We do not specifically test our A10809 product for use in cell culture. However, several papers cite use of this compound in cell culture, in the micromolar range.

      Helpful?

  3. Can I dissolve Product A10809, Apocynin, in water?

    1 answer

    1. According to the chemicals encyclopedia published by the Royal Society of Chemistry, this product is slightly soluble in cold water and freely soluble in hot water. One publication cites preparation of stock solutions of this compound in cell culture medium at 2.5 mg/mL. See Heigold and Bauer, J. Leukocyte Biol., 72, 554-562 (2002).

      Helpful?

  4. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  5. How can I store stock solutions of Product A10809, Apocynin?

    1 answer

    1. While we ourselves have not tested solution stability, one publication cites storage at -20°C of stock solutions of this compound in cell culture medium at 2.5 mg/mL (Heigold and Bauer, J. Leukocyte Biol., 72, 554-562 (2002).

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