803561
BMOE (bis-maleimidoethane)
Sinônimo(s):
1,1′-ethane-1,2-diylbis(1H-pyrrole-2,5-dione), N,N′-Ethylenebismaleimide, BMOE, Ethylenebismaleimide
Faça loginpara ver os preços organizacionais e de contrato
About This Item
Fórmula empírica (Notação de Hill):
C10H8N2O4
Número CAS:
Peso molecular:
220.18
Número MDL:
Código UNSPSC:
12352200
ID de substância PubChem:
NACRES:
NA.22
Formulário:
powder
Produtos recomendados
Formulário
powder
peso molecular
220.18
adequação da reação
reagent type: cross-linking reagent
condição de armazenamento
desiccated
solubilidade
DMSO or DMF: soluble
Condições de expedição
ambient
temperatura de armazenamento
2-8°C
cadeia de caracteres SMILES
O=C(C=CC1=O)N1CCN2C(C=CC2=O)=O
InChI
1S/C10H8N2O4/c13-7-1-2-8(14)11(7)5-6-12-9(15)3-4-10(12)16/h1-4H,5-6H2
chave InChI
PUKLCKVOVCZYKF-UHFFFAOYSA-N
Descrição geral
BMOE, BMB and BMH are homobifunctional, maleimide crosslinkers for conjugation between sulfhydryl groups (-SH). Such bismaleimide crosslinkers are commonly used to explore and characterize protein structure (i.e., oligomerization) or protein interactions. Because BMOE, BMB and BMH have the same reactivity but differ in length, the relative success of these three reagents in forming crosslinks between sites in a protein oligomer or interaction can assist in determining intra- and intermolecular distances.
Características e benefícios
- Reactive groups: maleimide (both ends)
- Reactive towards: sulfhydryl groups
- Short (8.0Å), sulfhydryl-to-sulfhydryl crosslinker, composed of maleimide groups and 7-atom spacer arm
- Shortest bismaleimide crosslinker available for close proximity crosslinking
- Water-insoluble—dissolve first in DMF or DMSO, then add to aqueous reaction buffers
- Noncleavable
Atenção
This product is sensitive to moisture. The vial is packaged in a resealable bag with a desiccant to reduce exposure to moisture. After cold storage, equilibrate the vial to room temperature before opening to reduce condensation inside the vial. Make fresh solutions. Storage of stock solutions is not recommended. After use, return the vial to the resealable bag. Close the bag and store the product at the recommended temperature.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Escolha uma das versões mais recentes:
Certificados de análise (COA)
Lot/Batch Number
Não está vendo a versão correta?
Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
Os clientes também visualizaram
Z Xie et al.
The Journal of biological chemistry, 275(34), 25959-25964 (2000-06-15)
The Vibrio parahaemolyticus sodium/glucose transporter (vSGLT) is a bacterial member of the SGLT gene family. Wild-type and mutant vSGLT proteins were expressed in Escherichia coli, and transport activity was measured in intact cells and plasma membrane vesicles. Two cysteine-less vSGLT
M A Stalteri et al.
Bioconjugate chemistry, 6(2), 179-186 (1995-03-01)
Cross-linked F(ab')2 fragments derived from PR1A3, a murine monoclonal antibody used in radioimmunoscintigraphy of colorectal tumors, were produced using the bifunctional reagent bismaleimidohexane (BMH) as follows: Digestion of PR1A3 with pepsin gave F(ab')2 fragments which were purified by ion-exchange chromatography.
Yong-Kook Kwon et al.
The Journal of cell biology, 163(2), 375-384 (2003-10-22)
A thiol-reactive membrane-associated protein (TRAP) binds covalently to the cytoplasmic domain of the human insulin receptor (IR) beta-subunit when cells are treated with the homobifunctional cross-linker reagent 1,6-bismaleimidohexane. Here, TRAP was found to be phospholipase C gamma1 (PLCgamma1) by mass
Kyoko Takebe et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 17(14), 2037-2047 (2003-11-05)
Epimorphin is a mesenchymal morphogen that has been shown to mediate epithelial-mesenchymal signaling interactions in various organs. We now show that epimorphin functions in hair follicle morphogenesis; using a novel ex vivo organ culture assay, we define a mechanism for
Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.
Entre em contato com a assistência técnica