663190

Ethyl 5-methylindole-2-carboxylate

97%

• Sinônimo(s): 5-Methylindole-2-carboxylic acid ethyl ester, NSC 30928
• Fórmula empírica (Notação de Hill): C₁₂H₁₃NO₂
• Número CAS: 16382-15-3
• Peso molecular: 203.24
• Número MDL: MFCD00022703
• Código UNSPSC: 12352100
• ID de substância PubChem: 24884618
• NACRES: NA.22

Propriedades

• Nível de qualidade: 100
• Ensaio: 97%
• Formulário: solid
• pf: 160-164 °C
• grupo funcional: ester
• cadeia de caracteres SMILES: CCOC(=O)c1cc2cc(C)ccc2[nH]1
• InChI: 1S/C12H13NO2/c1-3-15-12(14)11-7-9-6-8(2)4-5-10(9)13-11/h4-7,13H,3H2,1-2H3
• chave InChI: KMVFKXFOPNKHEM-UHFFFAOYSA-N

Descrição

Descrição geral

Ethyl 5-methylindole-2-carboxylate (5-Methylindole-2-carboxylic acid ethyl ester) is an indole derivative. Indole ring system is an important building block or intermediate in the synthesis of many pharmaceutical agents. It is formed during the Fischer indolization of ethyl pyruvate 2-[2-(methanesulfonyloxy)-4-methyl]phenylhydrazine.[1]

Aplicação

• Reactant for synthesis of oxazino[4,3-a]indoles via cascade addition-cyclization reactions
• Reactant for preparation of indolecarboxamides as cannabinoid CB1 receptor antagonists
• Reactant for preparation of indole-3-propionic acids as antiinflammatory and analgesic agents
• Reactant for Friedel-Crafts acylation with nitrobenzoyl chloride
• Reactant for oximation reactions

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)