638013

4-Diphenylphosphanylbenzoic acid, 2-(trimethylsilyl)ethyl ester solution

0.5 M in THF

• Fórmula empírica (Notação de Hill): C₂₄H₂₇O₂PSi
• Número CAS: 566190-45-2
• Peso molecular: 406.53
• Número MDL: MFCD07369722
• Código UNSPSC: 12352108
• ID de substância PubChem: 24882904

Propriedades

• adequação da reação: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• concentração: 0.5 M in THF
• densidade: 0.925 g/mL at 25 °C
• grupo funcional: phosphine
• cadeia de caracteres SMILES: C[Si](C)(C)CCOC(=O)c1ccc(cc1)P(c2ccccc2)c3ccccc3
• InChI: 1S/C24H27O2PSi/c1-28(2,3)19-18-26-24(25)20-14-16-23(17-15-20)27(21-10-6-4-7-11-21)22-12-8-5-9-13-22/h4-17H,18-19H2,1-3H3
• chave InChI: QTYUNPJLGFKKRV-UHFFFAOYSA-N

Descrição

Aplicação

4-Diphenylphosphanyl-benzoic acid 2-trimethylsilanyl-ethyl ester (DPPBE) was developed as an efficient alternative to triphenylphosphine in the Mitsunobu reaction since the phosphine oxide formed during the reaction can be easily removed during workup.

Reagent for:

• Synthesis of alkenes
• Methylation of aldehydes
• Mitsunobu reactions

Informações de segurança

• Pictogramas: GHS02,GHS08,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H225,H319,H335,H351
• Declarações de precaução: P210 - P280 - P305 + P351 + P338 - P370 + P378 - P403 + P235
• Classificações de perigo: Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Perigos de suplementos: EUH019
• Código de classe de armazenamento: 3 - Flammable liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): -4.0 °F - closed cup
• Ponto de fulgor (°C): -20 °C - closed cup