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47695

Sigma-Aldrich

Fmoc-Cys(Trt)-OH

≥95.0% (sum of enantiomers, HPLC)

Sinônimo(s):

N-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cysteine, Nα-Fmoc-S-trityl-L-cysteine

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About This Item

Fórmula empírica (Notação de Hill):
C37H31NO4S
Número CAS:
Peso molecular:
585.71
Beilstein:
4221286
Número MDL:
Código UNSPSC:
12352209
eCl@ss:
32160406
ID de substância PubChem:
NACRES:
NA.26
Preço e disponibilidade não estão disponíveis no momento.

Ensaio

≥95.0% (sum of enantiomers, HPLC)

atividade óptica

[α]20/D +16.0±2°, c = 1% in THF

adequação da reação

reaction type: Fmoc solid-phase peptide synthesis

pf

170-173 °C (lit.)

aplicação(ões)

peptide synthesis

grupo funcional

Fmoc

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

OC(=O)[C@H](CSC(c1ccccc1)(c2ccccc2)c3ccccc3)NC(=O)OCC4c5ccccc5-c6ccccc46

InChI

1S/C37H31NO4S/c39-35(40)34(38-36(41)42-24-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33)25-43-37(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28/h1-23,33-34H,24-25H2,(H,38,41)(H,39,40)/t34-/m0/s1

chave InChI

KLBPUVPNPAJWHZ-UMSFTDKQSA-N

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Descrição geral

Fmoc-Cys(Trt)-OH is an amino acid commonly used in the Fmoc solid-phase peptide synthesis. [1]

Aplicação

Fmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative used in peptide synthesis. Some of the examples are:
  • Synthesis of mono- and bi-functionalized platinum(IV) complexes to target angiogenic tumor vasculature.[2]
  • Synthesis of proteins through native chemical ligation of peptide hydrazides as thioester surrogates via solid-phase synthesis.[3]
  • Synthesis of glycoconjugates by conjugating reducing sugars to cysteine residues of peptides.[4]

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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Conjugated platinum (IV)? peptide complexes for targeting angiogenic tumor vasculature.
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N-Terminally free but C-terminally amidated peptides Pen-SSACS-NH

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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