414840
4-Nitro-3-pyrazolecarboxylic acid
98%
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About This Item
Fórmula empírica (Notação de Hill):
C4H3N3O4
Número CAS:
Peso molecular:
157.08
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:
NACRES:
NA.22
Produtos recomendados
Ensaio
98%
pf
223-225 °C (dec.) (lit.)
cadeia de caracteres SMILES
OC(=O)c1n[nH]cc1[N+]([O-])=O
InChI
1S/C4H3N3O4/c8-4(9)3-2(7(10)11)1-5-6-3/h1H,(H,5,6)(H,8,9)
chave InChI
ZMAXXOYJWZZQBK-UHFFFAOYSA-N
Descrição geral
4-Nitro-3-pyrazolecarboxylic acid is a pyrazole derivative. Catalytic activity of bimetallic colloids, composed of silver nanoparticles partially coated with Pd clusters, adsorbed on 4-nitro-3-pyrazolecarboxylic acid, has been investigated by Surface-enhanced Raman scattering (SERS) spectroscopy.[1] Effects of this pyrrazole on blood flow[2] and its palladium hydrogenation[3] has been studied.
Aplicação
4-Nitro-3-pyrazolecarboxylic acid may be used as a starting reagent for the synthesis of library of pyrazole derivatives, potential A3 adenosine receptor (A3AR) antagonists.[4]
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Órgãos-alvo
Respiratory system
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
dust mask type N95 (US), Eyeshields, Gloves
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SERS investigation on 4-nitro-3-pyrazolecarboxylic acid adsorbed on palladium-doped silver nanoparticles.
Pergolese B, et al.
Vibrational Spectroscopy, 48(1), 107-112 (2008)
Hydrogenation on Granular Palladium-containing Catalysts: II. Hydrogenation of Nitroheterocyclic Compounds
Russ. J. Org. Chem., 38, 269-271 (2002)
Jing Wei et al.
Neurochemistry international, 55(7), 637-642 (2009-06-23)
Adenosine is known to act as a neuromodulator by suppressing synaptic transmission in the central and peripheral nervous system. A(3) adenosine receptor (A(3)AR) antagonists were recently considered as potential drugs for the treatment of cardiac ischemia and inflammation diseases. To
Bo Xuan et al.
Acta pharmacologica Sinica, 23(8), 705-712 (2002-07-31)
Effects of C-nitropyrazoles and C-nitroazoles on ocular blood flow and retinal function recovery after ischemia have been studied. The compounds were tested on ocular blood flow of ocular hypertensive (40 mmHg) rabbit eyes with colored microsphere technique. They were also
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