362433

Diethyl (N-methoxy-N-methylcarbamoylmethyl)phosphonate

96%

• Sinônimo(s): N-Methoxy-N-methyl-2-(diethyl phosphono)acetamide, N-Methoxy-N-methyl-phosphonoacetamide diethyl ester, Diethyl N-methoxy-N-methylphosphonoacetamide, Diethylphosphonoacetic acid N-methyl-N-methoxyamide
• Fórmula linear: CH₃ON(CH₃)COCH₂P(O)(OC₂H₅)₂
• Número CAS: 124931-12-0
• Peso molecular: 239.21
• Beilstein: 1875865
• Número MDL: MFCD00134233
• Código UNSPSC: 12352108
• ID de substância PubChem: 24862312
• NACRES: NA.22

Propriedades

• Ensaio: 96%
• Formulário: liquid
• adequação da reação: reaction type: C-C Bond Formation
• índice de refração: n20/D 1.455 (lit.)
• p.e.: 90 °C/17 mmHg (lit.)
• densidade: 1.163 g/mL at 25 °C (lit.)
• grupo funcional: amine; phosphonate
• cadeia de caracteres SMILES: CCOP(=O)(CC(=O)N(C)OC)OCC
• InChI: 1S/C8H18NO5P/c1-5-13-15(11,14-6-2)7-8(10)9(3)12-4/h5-7H2,1-4H3
• chave InChI: WYLRYBDGIILFIR-UHFFFAOYSA-N

Descrição

Aplicação

Reactant for:

• Preparation of ring-expanded bryostatin analogs as antitumor agents
• Asymmertic synthesis of pinnatoxins A and G via diastereoselective Ireland-Claisen rearrangement, ring closing metathesis, and cyclization
• Rh2(II)-catalyzed nitro-group migration reactions
• Stereoselective synthesis of cyclohexanones via phase transfer catalyzed double addition reactions
• Stereoselective synthesis of (+)-polyrhacitide A via aldol reaction, Horner-Wardsworth-Emmons reaction, Evans acetal intramolecular oxa-Michael reaction and diastereoselective syn reduction reaction as the key steps
• Preparation of substituted furans via olefin cross-metathesis

Wittig carbonylating reagent.[1]

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H315,H319,H335
• Declarações de precaução: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 230.0 °F - closed cup
• Ponto de fulgor (°C): 110 °C - closed cup
• Equipamento de proteção individual: Eyeshields, Gloves, type ABEK (EN14387) respirator filter