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329967

Sigma-Aldrich

(+)-Usnic acid

98%

Sinônimo(s):

(+)-Usnic acid from Usnea dasypoga, 2,6-Diacetyl-7,9-dihydroxy-8,9b-dimethyldibenzofuran-1,3(2H,9bH)-dione

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5 G
R$ 660,00
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R$ 2.362,00

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Previsão de entrega em04 de abril de 2025


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5 G
R$ 660,00
25 G
R$ 2.362,00

About This Item

Fórmula empírica (Notação de Hill):
C18H16O7
Número CAS:
Peso molecular:
344.32
Beilstein:
96698
Número CE:
Número MDL:
Código UNSPSC:
12352106
ID de substância PubChem:
NACRES:
NA.22

R$ 660,00


Previsão de entrega em04 de abril de 2025


Solicite uma grande encomenda

Nível de qualidade

Ensaio

98%

Formulário

powder

atividade óptica

[α]25/D +488°, c = 0.7% in chloroform

pf

201-203 °C (lit.)

grupo funcional

ketone

cadeia de caracteres SMILES

C[C@](C1=C(O)C(C)=C(O)C(C(C)=O)=C1O2)(C(C3C(C)=O)=O)C2=CC3=O

InChI

1S/C18H16O7/c1-6-14(22)12(8(3)20)16-13(15(6)23)18(4)10(25-16)5-9(21)11(7(2)19)17(18)24/h5,22-24H,1-4H3/t18-/m1/s1

chave InChI

ICTZCAHDGHPRQR-GOSISDBHSA-N

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Descrição geral

(+)-Usnic acid is a bioactive compound mainly found as a secondary metabolite in lichens.[1]

Aplicação

(+)-Usnic acid has been used to study the following:
  • The mechanism of its antimicrobial activity in bacterial cells.[2]
  • Its ability as an antibiofilm agent against Group A Streptococci (GAS).[1]
  • Its ability as a potent anti-virulent compound against Candida albicans.[3]
  • The mechanism of its toxic effect on hepatocytes.[4]
  • Its ability to inhibit the motility of human lung cancer cells.[5]

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves


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Os clientes também visualizaram

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1 of 2

Sohaila Erfani et al.
Iranian journal of basic medical sciences, 23(9), 1225-1231 (2020-09-24)
Cerebral ischemia/reperfusion causes complex pathological mechanisms that lead to brain tissue damage. Usnic acid is a lichen secondary metabolite that has many different biological properties including anti-inflammatory and anti-oxidant activities. Therefore, the objective of the current study was to investigate
Michal Goga et al.
Ecology and evolution, 8(5), 2781-2787 (2018-03-14)
Lichens and mosses often share the same environmental conditions where they compete for substrate and other essential factors. Lichens use secondary metabolites as allelochemicals to repel surrounding plants and potential rivals. In mosses, endoreduplication leads to the occurrence of various
Inhibitory Activity of (+)-Usnic Acid against Non-Small Cell Lung Cancer Cell Motility.
Yang Y, et al.
PLoS ONE, 11(1), e0146575-e0146575 (2016)
Kunal Kumar et al.
Chemico-biological interactions, 315, 108898-108898 (2019-11-13)
Usnic acid, a dibenzofuran derivative found in many lichen species, is reported to have anticancer activity against human gastric cancer. We investigated the molecular alterations associated with anticancer effects of usnic acid against human gastric adenocarcinoma AGS and gastric carcinoma
Usnic acid inhibits biofilm formation and virulent morphological traits of Candida albicans.
Nithyanand P, et al.
Microbiological research, 179, 20-28 (2015)

Questions

1–2 of 2 Questions  
  1. Do you offer any interpretation of the IR spectrum of Product 329967, (+)-Usnic acid?

    1 answer
    1. Although we do not perform any detailed analysis of IR spectrum as part of our routine QC testing for this product, we can say that the broad stretch around  3000 cm-1is due to hydrogen-bonded hydroxyl (OH) groups and the band at 1700 cm-1 is due to the carbonyl (C=O).

      Helpful?

  2. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

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