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Dianhydro-D-glucitol

98%

Sinônimo(s):

1,4:3,6-Dianhydro-D-sorbitol, D-Isosorbide

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100 G
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Disponível para enviar em22 de abril de 2025Detalhes


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100 G
R$ 550,00
500 G
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About This Item

Fórmula empírica (Notação de Hill):
C6H10O4
Número CAS:
Peso molecular:
146.14
Beilstein:
80510
Número CE:
Número MDL:
Código UNSPSC:
12352201
ID de substância PubChem:
NACRES:
NA.22

R$ 550,00


Disponível para enviar em22 de abril de 2025Detalhes


Solicite uma grande encomenda

Nível de qualidade

Ensaio

98%

Formulário

solid

atividade óptica

[α]20/D +45.2°, c = 3 in H2O

pf

60-63 °C (lit.)

cadeia de caracteres SMILES

O[C@H]1CO[C@@H]2[C@H](O)CO[C@H]12

InChI

1S/C6H10O4/c7-3-1-9-6-4(8)2-10-5(3)6/h3-8H,1-2H2/t3-,4+,5-,6-/m1/s1

chave InChI

KLDXJTOLSGUMSJ-JGWLITMVSA-N

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Aplicação

Dianhydro-D-glucitol is a greener ingredient widely used as a monomer and building block for a variety of polymers and functional materials, for medical and pharmaceutical applications.[1][2][3] It is also used as a fuel or fuel additive.[1]
Applications include:
  • Preparation of renewable polyesters for coating applications.[4]
  • Synthesis of isosorbide esters such as oligo(isosorbide adipate) (OSA), oligo(isosorbide suberate) (OSS), and isosorbide dihexanoate (SDH) as renewable alternatives to phthalate plasticizers.[5]
  • Synthesis of biodegradable porous polyurethane scaffolds for tissue repair and regeneration.[2]
  • Synthesis of the aspirin prodrug, isosorbide-2,5-diaspirinate (ISDA).[3]

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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Neal T Wasserman et al.
Veterinary ophthalmology, 16(1), 20-24 (2012-04-20)
To evaluate and compare the effects of oral isosorbide and glycerol on intraocular pressure (IOP), serum osmolality (SOSM), and blood glucose (BG) in normal dogs. Ten normal dogs were administered an oral dose of either isosorbide (1.5 g/kg), glycerol (1.5g/kg)
Jonathan Lai et al.
ChemSusChem, 4(8), 1104-1111 (2011-07-19)
The telomerisation of 1,3-butadiene with a Pd/TPPTS catalytic system in water or an organic solvent was used for the synthesis of C8 ethers from isosorbide, an agro-based diol. The use of water/oil biphasic reaction conditions allowed the selective synthesis of
Discovery of a ?true? aspirin prodrug.
Moriarty LM, et al.
Journal of Medicinal Chemistry, 51(24), 7991-7999 (2008)
Bleeding from ruptured oesophageal varices: propranolol for primary prevention.
Prescrire international, 21(125), 73-77 (2012-03-21)
Ying Xia et al.
ChemSusChem, 4(3), 386-391 (2011-01-25)
A series of soybean oil-based amide diol-isosorbide waterborne polyurethane-urea (PUU) dispersions have been successfully prepared, with amounts of isosorbide ranging from 0 to 20 wt % of the total diol content. The thermal and mechanical properties of the resulting PUU films have

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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