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263893

Sigma-Aldrich

Phenoxazine

≥99%, purified by sublimation

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About This Item

Fórmula empírica (Notação de Hill):
C12H9NO
Número CAS:
135-67-1
Peso molecular:
183.21
Beilstein:
143234
Número CE:
205-210-8
Número MDL:
MFCD00005014
Código UNSPSC:
12352100
ID de substância PubChem:
24855892

Ensaio

≥99%

purificado por

sublimation

pf

156-159 °C (lit.)

solubilidade

benzene: freely soluble(lit.)
chloroform: freely soluble(lit.)
diethyl ether: freely soluble(lit.)
ethanol: freely soluble(lit.)
petroleum ether: very slightly soluble(lit.)

cadeia de caracteres SMILES

N1c2ccccc2Oc3ccccc13

InChI

1S/C12H9NO/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H

chave InChI

TZMSYXZUNZXBOL-UHFFFAOYSA-N

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Descrição geral

Phenoxazine dyes, including several Nile blue analogs, are known to localize selectively in animal tumors.

Aplicação

Phenoxazine is a tricyclic 2′deoxycytidine analog that has been used to improve stacking interactions between heterocycles of oligonucleotide/RNA hybrids and to enhance cellular uptake.

Código de classe de armazenamento

13 - Non Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
00924MD
13727MU
18118DB
07505AG
06008EY

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10-Phenylphenothiazine ≥95%

Sigma-Aldrich

903167

10-Phenylphenothiazine

10,11-Dihydro-5H-dibenz[b,f]azepine 97%

Sigma-Aldrich

I1308

10,11-Dihydro-5H-dibenz[b,f]azepine

Carbazole ≥95% (GC)

Sigma-Aldrich

C5132

Carbazole

Acridine ≥96.5% (HPLC)

Sigma-Aldrich

A23609

Acridine

W M Flanagan et al.
Nature biotechnology, 17(1), 48-52 (1999-01-27)
One of the major barriers to the development of antisense therapeutics has been their poor bioavailability. Numerous oligonucleotide modifications have been synthesized and evaluated for enhanced cellular permeation with limited success. Phenoxazine, a tricyclic 2' deoxycytidine analog, was designed to
C W Lin et al.
Cancer research, 51(4), 1109-1116 (1991-02-15)
The overall goal of our research is to develop effective new photosensitizers for tumor-selective photodynamic therapy. Phenoxazine dyes, including several Nile blue analogues, are known to localize selectively in animal tumors. Structural modifications yielded several series of analogues with substantially
Frédéric Bruyneel et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 15(33), 8283-8295 (2009-07-23)
Laccases are members of the blue copper oxidases family found in nature. They commonly oxidise a wide range of phenol and aniline derivatives, which in turn are involved in oxidative coupling reactions. Yet, laccases remain rarely described as biocatalysts in
Karina Mondragón-Vásquez et al.
Chemical communications (Cambridge, England), (44)(44), 6726-6728 (2009-11-04)
N(6)-(N'-Arylcarbamoyl)-2'-deoxyadenosine-H-phosphonates displayed molecular recognition towards cationic phenothiazinium and phenoxazinium dyes in aqueous solutions; studies have shown that binding is driven mainly by aromatic interactions and that size and shape-complementarity of the aromatic rings in host and guest provides selectivity.
Riyad Ahmed Al Okab
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 103, 333-337 (2012-12-25)
Green analytical methods using Cisapride (CPE) as green analytical reagent was investigated in this work. Rapid, simple, and sensitive spectrophotometric methods for the determination of bromate in water sample, bread and flour additives were developed. The proposed methods based on
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