127906
5-Amino-1,3,4-thiadiazole-2-thiol
95%
Sinônimo(s):
2-Amino-5-mercapto-1,3,4-thiadiazole
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About This Item
Fórmula empírica (Notação de Hill):
C2H3N3S2
Número CAS:
Peso molecular:
133.20
Beilstein:
81728
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:
NACRES:
NA.22
Produtos recomendados
Ensaio
95%
pf
235 °C (dec.) (lit.)
cadeia de caracteres SMILES
Nc1nnc(S)s1
InChI
1S/C2H3N3S2/c3-1-4-5-2(6)7-1/h(H2,3,4)(H,5,6)
chave InChI
GDGIVSREGUOIJZ-UHFFFAOYSA-N
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Aplicação
5-amino-1,3,4-thiadiazole-2-thiol was used to prepare new amines exhibiting anti-convulsant activity[1].
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Órgãos-alvo
Respiratory system
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
dust mask type N95 (US), Eyeshields, Gloves
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Rodica Olar et al.
Materials (Basel, Switzerland), 13(20) (2020-10-22)
The derivatives 5,7-dimethyl[1,3,4]thiadiazolo[3,2-a]pyrimidin-4-ium-2-thiolate (1) and 7-methyl-5-phenyl[1,3,4]thiadiazolo[3,2-a]pyrimidin-4-ium-2-thiolate (2) were fully characterized by single-crystal X-ray diffraction. Their supramolecular structure is built through both π-π stacking and C=S-π interactions for both compounds. The embedment of the tested compounds into Fe3O4@C18 core-shell nanocoatings increased
Mohammad Hossein Ghanbari et al.
Mikrochimica acta, 186(9), 641-641 (2019-08-25)
A nanocomposite was prepared with reduced graphene oxide, gold nanoparticles and an electropolymerized film made from 2-amino-5-mercapto-1,3,4-thiadiazole. An electrochemical sensor for doxorubicin (DOX) was constructed by modifying a glassy carbon electrode (GCE) with the nanocomposite. The modified GCE was studied
Chun-Wei Lee et al.
Biosensors & bioelectronics, 133, 215-222 (2019-04-06)
Early diagnosis of bacterial infections is crucial to improving survival rates by enabling treatment with appropriate antibiotics within the first few hours of infection. This paper presents a highly sensitive amperometric biosensor for the detection of several pathogenic bacterial cells
M Kavlakova et al.
Arzneimittel-Forschung, 62(12), 599-602 (2012-10-25)
The coordination properties of Pt(II) with 5-amino-1,3,4-thiadiazole-2-thiol [CAS 2349-67-9] (L 1 ) and its novel violurate adduct (L 2 ), both in solution and in solid state, are studied by means of conventional IR-spectroscopy, single crystal X-ray diffraction and thermal
Mohammad Yusuf et al.
Chemical biology & drug design, 81(5), 666-673 (2013-01-31)
New imines, derived from aromatic aldehyde, chalcones and 5-amino-1,3,4-thiadiazole-2-thiol exhibited promising anti-convulsant activity which is explained through chemo-biological interactions at receptor site producing the inhibition of human Carbonic Anhydrase-II enzyme (hCA-II) through the proposed pharmacophore model at molecular levels as
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