112801
Pyridoxine hydrochloride
98%
Sinônimo(s):
Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B6 hydrochloride
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About This Item
Fórmula empírica (Notação de Hill):
C8H11NO3 · HCl
Número CAS:
Peso molecular:
205.64
Beilstein:
3632435
Número CE:
Número MDL:
Código UNSPSC:
12352005
ID de substância PubChem:
Produtos recomendados
Ensaio
98%
Formulário
powder
cor
white to off-white
pf
214-215 °C (lit.)
cadeia de caracteres SMILES
Cl[H].Cc1ncc(CO)c(CO)c1O
InChI
1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H
chave InChI
ZUFQODAHGAHPFQ-UHFFFAOYSA-N
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Descrição geral
Pyridoxine hydrochloride is a water soluble vitamin. It is available through dietary sources like, meat, fish, nuts, vegetables and fruits.[1]
Ações bioquímicas/fisiológicas
Pyridoxine/vitamin B6 is implicated in cellular metabolism, fatty acid biosynthesis, amino acid biosynthesis and catabolism. It is also implicated in the production of neurotransmitters, chlorophyll and plant hormones. Pyridoxine acts as a cofactor for several biochemical reactions.[2] Pyridoxine deficiency is associated with peripheral neuropathy.[3] Pyridoxine hydrochloride is available in parenteral and oral formulations.[1]
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Vitamin B6 and its role in cell metabolism and physiology
Parra M, et al.
Cells, 7(7), 84-84 (2018)
Ilan Matok et al.
Journal of clinical pharmacology, 53(3), 334-338 (2013-02-28)
Although Diclectin (doxylamine/pyridoxine delayed-released combination) is widely used in Canada, its pharmacokinetics (PK) during pregnancy has never been described. The objective of this study was to compare the PK of doxylamine/pyridoxine delayed-released combination in pregnant versus nonpregnant women. The apparent
Sonia Fargue et al.
Biochimica et biophysica acta, 1832(10), 1776-1783 (2013-04-20)
Primary hyperoxaluria type 1 (PH1) is a rare hereditary calcium oxalate kidney stone disease caused by a deficiency of the liver-specific pyridoxal-phosphate-dependent peroxisomal enzyme alanine:glyoxylate aminotransferase (AGT). About one third of patients are responsive to pharmacological doses of pyridoxine (vitamin
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