TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
Sinônimos:
AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII
Espécies:
Human TGFBR2 (7048), Mouse Tgfbr2 (21813), Rat Tgfbr2 (81810), Horse TGFBR2 (100033860), Zebrafish tgfbr2 (30739), chicken TGFBR2 (396399), domestic guinea pig Tgfbr2 (100718284), dog TGFBR2 (477039), domestic cat TGFBR2 (101091725), cow TGFBR2 (535376) ...Mais
ID UniProtKB:
ID do gene:
- Human(7048) Summary: This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
- Mouse(21813) transforming growth factor, beta receptor II
- Rat(81810) transforming growth factor, beta receptor II
- Horse(100033860) transforming growth factor, beta receptor II (70/80kDa)
- Zebrafish(30739) transforming growth factor, beta receptor II
- chicken(396399) transforming growth factor, beta receptor II (70/80kDa)
- domestic guinea pig(100718284) transforming growth factor, beta receptor II (70/80kDa)
- dog(477039) transforming growth factor, beta receptor II (70/80kDa)
- domestic cat(101091725) transforming growth factor, beta receptor II (70/80kDa)
- cow(535376) transforming growth factor, beta receptor II (70/80kDa)
- sheep(494191) transforming growth factor, beta receptor II (70/80kDa)
- naked mole-rat(101704397) transforming growth factor, beta receptor II (70/80kDa)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Número do produto
Descrição
Espécies
Human TGFBR2 / TGF-beta Receptor Type-2 ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Espécies
human
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-TGFBR2 antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TGF β Receptor II antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
western blot
western blot
Anti-TGFBR2 Antibody, clone 1N11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human
Aplicação
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-phospho-TGF β Receptor II (pSer225/250) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry
immunohistochemistry
Anti-TGFBR2 antibody produced in rabbit, IgG fraction of antiserum,
Reatividade de espécies
human, rabbit
Aplicação
western blot
Proteins
Número do produto
Descrição
Espécies
TGFβR2 (190-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human
Transforming Growth Factor-β2 human, TGF-β2, recombinant, expressed in NSO cells, powder, suitable for cell culture,
Espécies
human
esiRNA
Número do produto
Descrição
Espécies