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RNF20

ring finger protein 20, E3 ubiquitin protein ligase

Sinônimos:
BRE1, BRE1A, hBRE1
Espécies:
ID UniProtKB:
ID do gene:
  • Human(56254) Summary: The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012]
  • Mouse(109331) ring finger protein 20
  • Rat(313216) ring finger protein 20, E3 ubiquitin protein ligase
  • Zebrafish(402838) ring finger protein 20, E3 ubiquitin protein ligase
  • domestic cat(101097522) ring finger protein 20, E3 ubiquitin protein ligase
  • cow(513326) ring finger protein 20
  • dog(474788) ring finger protein 20, E3 ubiquitin protein ligase
  • chicken(427310) ring finger protein 20, E3 ubiquitin protein ligase
  • naked mole-rat(101711656) ring finger protein 20, E3 ubiquitin protein ligase
  • domestic guinea pig(100717191) ring finger protein 20, E3 ubiquitin protein ligase
  • Domestic Rabbit(100340973) ring finger protein 20, E3 ubiquitin protein ligase
  • Horse(100054384) ring finger protein 20, E3 ubiquitin protein ligase
  • sheep(101121065) ring finger protein 20, E3 ubiquitin protein ligase

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-RNF20 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
Anti-RNF20, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Monoclonal Anti-RNF20 antibody produced in mouse, clone 1C6, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot
Anti-Rnf20 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
Anti-RNF20 Antibody, clone 8N4O8, Rabbit Monoclonal, ,
Reatividade de espécies
mouse
Aplicação
western blot

Proteins

Número do produto
Descrição
Espécies
RNF20 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human RNF20,
Espécies
human