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Merck

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Sinônimos:
COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
Espécies:
ID UniProtKB:
ID do gene:
  • Human(5743) Summary: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
  • Mouse(19225) prostaglandin-endoperoxide synthase 2
  • Rat(29527) prostaglandin-endoperoxide synthase 2
  • Goat(100860905) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • cow(282023) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Horse(791253) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic cat(100126581) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • dog(442942) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Domestic Rabbit(100009248) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • sheep(443460) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • naked mole-rat(101704771) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • chicken(396451) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic guinea pig(100135607) prostaglandin-endoperoxide synthase 2

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ELISA

Número do produto
Descrição
Espécies
Human COX-2 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-COX2/PTGS2 Antibody, clone 2V7G8, Rabbit Monoclonal, ,
Reatividade de espécies
mouse
Aplicação
immunohistochemistry
western blot
Anti-COX2 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Cox2 antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-COX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
Anti-COX-2 antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM348, purified immunoglobulin,
Reatividade de espécies
human
Aplicação
immunohistochemistry

Small Molecule - Blocker

Número do produto
Descrição
Espécies
N-p-Tosyl-L-phenylalanine chloromethyl ketone, ≥97% (TLC), powder,
Espécies
human

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Carprofen, ≥97% (HPLC),
Espécies
human
Aceclofenac, ≥98% (HPLC),
Espécies
human
Meloxicam sodium salt hydrate, ≥98% (HPLC),
Espécies
human
Carprofen, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
Carprofen, VETRANAL®, analytical standard,
Espécies
human

Proteins

Número do produto
Descrição
Espécies
Cyclooxygenase 2 human, ≥70% (SDS-PAGE), recombinant, expressed in insect cells, aqueous solution, ≥8000 units/mg protein,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Ptgs2,
Espécies
mouse
MISSION® esiRNA, targeting human PTGS2,
Espécies
human