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Merck

PIK3C2A

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha

Sinônimos:
CPK, PI3-K-C2(ALPHA), PI3-K-C2A
Espécies:
ID UniProtKB:
ID do gene:
  • Human(5286) Summary: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008]
  • Mouse(18704) phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide
  • Rat(361632) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
  • sheep(101114899) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
  • Zebrafish(571356) phosphoinositide-3-kinase, class 2, alpha polypeptide
  • domestic cat(101096512) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
  • cow(537790) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
  • chicken(423070) phosphoinositide-3-kinase, class 2, alpha polypeptide
  • naked mole-rat(101702206) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
  • Domestic Rabbit(100340704) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
  • Horse(100056431) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
  • dog(485399) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
  • domestic guinea pig(100722144) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-PIK3C2A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-PIK3C2A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
Anti-PI3KC2A (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot
Anti-PIK3C2A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human, mouse
Aplicação
ELISA
immunohistochemistry
ANTI-PI3KC2A(N-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot

Proteins

Número do produto
Descrição
Espécies
PIK3C2A, active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human PIK3C2A,
Espécies
human
MISSION® esiRNA, targeting mouse Pik3c2a,
Espécies
mouse