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Merck

PARP1

poly (ADP-ribose) polymerase 1

Sinônimos:
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1
Espécies:
ID UniProtKB:
ID do gene:
  • Human(142) Summary: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11545) poly (ADP-ribose) polymerase family, member 1
  • Rat(25591) poly (ADP-ribose) polymerase 1
  • Thale Cress(817690) poly [ADP-ribose] polymerase 2
  • chicken(396199) poly (ADP-ribose) polymerase 1
  • Zebrafish(560788) poly (ADP-ribose) polymerase family, member 1
  • sheep(100135697) poly (ADP-ribose) polymerase 1
  • domestic cat(101081434) poly (ADP-ribose) polymerase 1
  • Horse(100058523) poly (ADP-ribose) polymerase 1
  • dog(490385) poly (ADP-ribose) polymerase 1
  • domestic guinea pig(100733925) poly (ADP-ribose) polymerase 1
  • naked mole-rat(101703207) poly (ADP-ribose) polymerase 1
  • cow(286764) poly (ADP-ribose) polymerase 1

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-PARP (Cleaved-Asp214) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse
Aplicação
ELISA
western blot
Anti-Poly ADP-ribose Antibody, clone 10H, clone 10H, from mouse,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunoprecipitation (IP)

western blot
Monoclonal Anti-PARP1 antibody produced in mouse, clone 3G4, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence

western blot
Anti-PARP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-cleaved PARP-1 Antibody, clone 2G13 Antibody, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human, monkey
Aplicação
flow cytometry
immunocytochemistry

immunohistochemistry

western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Benzamide, 99%,
Espécies
human
3-Aminobenzamide, ≥99% (TLC),
Espécies
mouse
Benzamide, purified by sublimation, ≥99.5%,
Espécies
human
6-(5H)-Phenanthridinone, technical grade,
Espécies
human
Nicotinamide, BioReagent, suitable for cell culture, suitable for insect cell culture,
Espécies
human

Proteins

Número do produto
Descrição
Espécies
PARP-1 human, recombinant, expressed in E. coli,
Espécies
human
PARP1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Espécies
human
Monoclonal Anti-PARP1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2220, purified immunoglobulin, buffered aqueous glycerol solution,
Espécies
human
Monoclonal Anti-PARP1, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2209, purified immunoglobulin, buffered aqueous glycerol solution,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human PARP1,
Espécies
human
MISSION® esiRNA, targeting mouse Parp1,
Espécies
mouse