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Merck

MYC

v-myc avian myelocytomatosis viral oncogene homolog

Sinônimos:
MRTL, MYCC, bHLHe39, c-Myc
Espécies:
ID UniProtKB:
ID do gene:
  • Human(4609) Summary: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17869) myelocytomatosis oncogene
  • Rat(24577) myelocytomatosis oncogene
  • chicken(420332) v-myc myelocytomatosis viral oncogene homolog
  • dog(403924) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic cat(100379628) v-myc myelocytomatosis viral oncogene homolog (avian)
  • cow(511077) v-myc myelocytomatosis viral oncogene homolog (avian)
  • sheep(443447) v-myc myelocytomatosis viral oncogene homolog (avian)
  • Domestic Rabbit(100327265) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic guinea pig(100724557) v-myc myelocytomatosis viral oncogene homolog (avian)

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ELISA

Número do produto
Descrição
Espécies
Human c-Myc ELISA, for serum, plasma and cell culture supernatants,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Monoclonal Anti-c-Myc tag Biotin produced in mouse, ,
Reatividade de espécies
Aplicação
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-c-Myc antibody, Mouse monoclonal, clone 9E10, purified from hybridoma cell culture,
Reatividade de espécies
human
Aplicação
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

microarray

western blot
Anticorpo anticauda Myc, clone 4A6, clone 4A6, Upstate®, from mouse,
Reatividade de espécies
human
Aplicação
ChIP
immunocytochemistry

immunofluorescence

immunoprecipitation (IP)

western blot
Anti-c-Myc antibody produced in rabbit, ~0.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
immunocytochemistry
immunofluorescence

immunoprecipitation (IP)

microarray

western blot
Anticorpo anticauda Myc, clone 4A6, clone 4A6, Upstate®, from mouse,
Reatividade de espécies
human
Aplicação
immunocytochemistry
immunofluorescence

immunoprecipitation (IP)

western blot

Proteins

Número do produto
Descrição
Espécies
C-myc, proto oncogene human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human MYC,
Espécies
human
MISSION® esiRNA, targeting mouse Myc,
Espécies
mouse