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Merck

IL12A

interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

Sinônimos:
CLMF, IL-12A, NFSK, NKSF1, P35
Espécies:
ID UniProtKB:
ID do gene:
  • Human(3592) Summary: This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]
  • Mouse(16159) interleukin 12a
  • Rat(84405) interleukin 12A
  • domestic guinea pig(100379543) interleukin 12a
  • chicken(407090) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • Zebrafish(445410) interleukin 12a
  • Horse(100034215) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • domestic cat(493741) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • dog(403977) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • cow(281856) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • Goat(100861293) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • sheep(443064) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • naked mole-rat(101701392) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

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ELISA

Número do produto
Descrição
Espécies
Human IL-12 p70 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espécies
human
Mouse IL-12 P40/70 ELISA Kit, for serum, plasma and cell culture supernatant,
Espécies
mouse
Rhesus Macaque IL12A / IL12B ELISA Kit, ,
Espécies
Porcine IL12A / IL12B ELISA Kit, ,
Espécies

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-IL-12A Antibody, clone 1G10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
baboon, bovine, canine, feline, goat, human, monkey, mouse, porcine, sheep
Aplicação
affinity binding assay
flow cytometry

western blot
Anti-Interleukin-12 antibody produced in goat, IgG fraction of antiserum,
Reatividade de espécies
mouse
Aplicação
neutralization
western blot
Anti-Interleukin-12 antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
Reatividade de espécies
human
Aplicação
neutralization
Anti-IL-12 alpha Antibody, from rabbit, purified by affinity chromatography,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot

Proteins

Número do produto
Descrição
Espécies
IL-12 human, recombinant, expressed in CHO cells, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Espécies
human
IL-12 from mouse, recombinant, expressed in CHO cells, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Espécies
mouse
IL-35 (mouse): FC (human), recombinant, expressed in CHO cells,
Espécies
mouse
Interleukin-12 human, ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Espécies
human
Interleukin-12 from mouse, ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Espécies
mouse

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Il12a,
Espécies
mouse
MISSION® esiRNA, targeting human IL12A,
Espécies
human