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Merck

CSF1R

colony stimulating factor 1 receptor

Sinônimos:
C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R
Espécies:
ID UniProtKB:
ID do gene:
  • Human(1436) Summary: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq, Jul 2008]
  • Mouse(12978) colony stimulating factor 1 receptor
  • Rat(307403) colony stimulating factor 1 receptor
  • domestic guinea pig(100726053) colony stimulating factor 1 receptor
  • naked mole-rat(101719513) colony stimulating factor 1 receptor
  • sheep(101109969) colony stimulating factor 1 receptor
  • cow(509418) colony stimulating factor 1 receptor
  • domestic cat(493706) colony stimulating factor 1 receptor
  • Horse(100060422) colony stimulating factor 1 receptor
  • dog(489188) colony stimulating factor 1 receptor
  • chicken(396406) colony stimulating factor 1 receptor

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ELISA

Número do produto
Descrição
Espécies
Human CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit, ,
Espécies
human
Phosphotyrosine CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit, ,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-CSF1R antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-CSF1R antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
canine, human, mouse, rat
Aplicação
ELISA
western blot
Anti-CSF-1R/CD115 Antibody clone FER216, clone FER216, from mouse,
Reatividade de espécies
human
Aplicação
western blot
Anti-CSFR antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence

immunohistochemistry
Anti-CSF-1R antibody, Rabbit monoclonal, clone SP211, recombinant, expressed in proprietary host, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Sunitinib malate, ≥98% (HPLC),
Espécies
human
Pazopanib, ,
Espécies
human

Proteins

Número do produto
Descrição
Espécies
FMS (539-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Csf1r,
Espécies
mouse
MISSION® esiRNA, targeting human CSF1R,
Espécies
human