BACE1
beta-site APP-cleaving enzyme 1
Sinônimos:
ASP2, BACE, HSPC104
Espécies:
Human BACE1 (23621), Mouse Bace1 (23821), Rat Bace1 (29392), Horse BACE1 (100071137), naked mole-rat Bace1 (101701890), sheep BACE1 (101119667), dog BACE1 (489390), cow BACE1 (614333), chicken BACE1 (419768), Zebrafish bace1 (403005) ...Mais
ID UniProtKB:
ID do gene:
- Human(23621) Summary: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
- Mouse(23821) beta-site APP cleaving enzyme 1
- Rat(29392) beta-site APP cleaving enzyme 1
- Horse(100071137) beta-site APP-cleaving enzyme 1
- naked mole-rat(101701890) beta-site APP-cleaving enzyme 1
- sheep(101119667) beta-site APP-cleaving enzyme 1
- dog(489390) beta-site APP-cleaving enzyme 1
- cow(614333) beta-site APP-cleaving enzyme 1
- chicken(419768) beta-site APP-cleaving enzyme 1
- Zebrafish(403005) beta-site APP-cleaving enzyme 1
- domestic cat(101086840) beta-site APP-cleaving enzyme 1
- domestic guinea pig(100135485) beta-site APP cleaving enzyme 1
- Domestic Rabbit(100343442) beta-site APP-cleaving enzyme 1
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ELISA
Número do produto
Descrição
Espécies
Activity Assay
Número do produto
Descrição
Espécies
β-Secretase (BACE1) Activity Detection Kit (Fluorescent), 1 kit sufficient for 250 reactions,
Espécies
human
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-BACE1 Antibody, clone 3D5, ,
Reatividade de espécies
human, mouse
Aplicação
ELISA
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-BACE Antibody, CT, clone 61-3E7, clone 61-3E7, Chemicon®, from mouse,
Reatividade de espécies
human, mouse, primate, rat
Aplicação
immunoprecipitation (IP)
western blot
western blot
Anti-BACE 1, N-Terminus (46-62) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot
Anti-BACE1 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicação
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-BACE Antibody, Chemicon®, from rabbit,
Reatividade de espécies
human, mouse
Aplicação
western blot
Small Molecule - Inhibitor
Kits
Número do produto
Descrição
Espécies
β-Secretase (BACE1) Activity Detection Kit (Fluorescent), 1 kit sufficient for 250 reactions,
Espécies
human
Proteins
Número do produto
Descrição
Espécies
β-Secretase human, recombinant, expressed in HEK 293 cells (C-terminal FLAG tagged), ≥10,000 units/mg protein,
Espécies
human