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Key Documents

MAK079

Sigma-Aldrich

Creatine Assay Kit

sufficient for 100 colorimetric or fluorometric tests

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About This Item

Code UNSPSC :
12161503
Nomenclature NACRES :
NA.84

Utilisation

sufficient for 100 colorimetric or fluorometric tests

Application(s)

cosmetics
food and beverages

Méthode de détection

colorimetric
fluorometric

Maladie(s) pertinente(s)

neurological disorders; genitourinary disorders

Température de stockage

−20°C

Description générale

Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.

Application

Creatine Assay Kit has been used to analyze the creatine content in samples.

Adéquation

Suitable for the measurement of creatine in biological fluids including serum, urine, CSF etc.

Principe

In this assay, Creatine concentration is determined by a coupled enzyme reaction, which results in a colorimetric (570 nm)/fluorometric (λex = 535em/λ = 587 nm) product, proportional to the creatine present.

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Réf. du produit
Description
Tarif

Mentions de danger

Conseils de prudence

Classification des risques

Aquatic Chronic 3

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3


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Stanniocalcin-1 protects a mouse model from renal ischemia-reperfusion injury by affecting ROS-mediated multiple signaling pathways.
Liu D, et al.
International Journal of Molecular Sciences, 17(7), 1051-1051 (2016)
Sandra D Chanez-Paredes et al.
Methods in molecular biology (Clifton, N.J.), 2367, 249-271 (2021-04-09)
The intestinal barrier is an essential component of innate host defense. The single layer of epithelial cells that line the intestine must balance barrier function with both active, transcellular and diffusive, paracellular transport. Tight junctions, which link adjacent cells, form
Adam Zajac et al.
Nutrients, 12(10) (2020-10-02)
The aim of the study was to evaluate the effects of 16 weeks of a low dose of magnesium creatine chelate supplementation on repeated sprint ability test (RAST) results in elite soccer players. Twenty well-trained soccer players participated in the
Paul Ikgan Sia et al.
Investigative ophthalmology & visual science, 60(13), 4360-4377 (2019-10-22)
To investigate the neuroprotective properties of creatine in the retina using in vitro and in vivo models of injury. Two different rat retinal culture systems (one containing retinal ganglion cells [RGC] and one not) were subjected to either metabolic stress
Aslaug Drotningsvik et al.
The British journal of nutrition, 120(7), 740-750 (2018-08-30)
Obesity increases the risk for developing kidney disease, and protection of kidneys through changes in diet should be investigated. Fish intake has been associated with reduced risk of developing kidney disease; therefore, we wanted to investigate whether cod protein intake

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