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M2172

Sigma-Aldrich

1-Thioglycérol

BioXtra, ≥97%

Synonyme(s) :

α-Monothioglycérol, α-Thioglycérol, 3-Mercapto-1,2-propanediol

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About This Item

Formule linéaire :
HSCH2CH(OH)CH2OH
Numéro CAS:
96-27-5
Poids moléculaire :
108.16
Numéro Beilstein :
1732046
Numéro CE :
202-495-0
Numéro MDL:
MFCD00004879
Code UNSPSC :
12352211
ID de substance PubChem :
24896709
Nomenclature NACRES :
NA.25

Gamme de produits

BioXtra

Pureté

≥97%

Forme

liquid

Impuretés

≤0.0005% Phosphorus (P)

Résidus de calcination

≤0.1%

Indice de réfraction

n20/D 1.527 (lit.)

Point d'ébullition

118 °C/5 mmHg (lit.)

Densité

1.25 g/mL at 25 °C (lit.)

Traces de cations

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.02%
Pb: ≤0.001%
Zn: ≤0.0005%

Température de stockage

2-8°C

Chaîne SMILES 

OCC(O)CS

InChI

1S/C3H8O2S/c4-1-3(5)2-6/h3-6H,1-2H2

Clé InChI

PJUIMOJAAPLTRJ-UHFFFAOYSA-N

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Catégories apparentées

Description générale

1-Thioglycerol stimulates the synthesis of porphyrin in aerobically growing Escherichia coli. It is an inhibitor of glycerol kinase activity in vitro and in situ.

Application

It has been used in a study to assess thiol-sensitive genes and promoters of Escherichia coli.

Notes préparatoires

This product is miscible in ethanol (1 ml/ml, 50%, v/v), yielding a clear, colorless solution. It is also miscible in water (0.1 M).

Pictogrammes

Skull and crossbones
GHS06

Mention d'avertissement

Danger

Mentions de danger

H302,H311 + H331,H315,H317

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Skin Irrit. 2 - Skin Sens. 1B

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

210.2 °F - closed cup

Point d'éclair (°C)

99 °C - closed cup

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

W K Seltzer et al.
Life sciences, 39(16), 1417-1424 (1986-10-20)
The infantile form of glycerol kinase (GK) deficiency (McKusick No. 30703) (1) is characterized by adrenal cortical insufficiency, adrenal hypoplasia and developmental delay. The underlying biochemical mechanism(s) responsible for the observed clinical presentations are undetermined. Pursuant to our examination of
G T Javor
Journal of bacteriology, 171(10), 5607-5613 (1989-10-01)
The effect of 1-thioglycerol on the expression of genes of Escherichia coli was investigated. Pulse-labeled proteins from aerobically growing, 1-thioglycerol-treated E. coli were separated by two-dimensional gel electrophoresis, and their radioactivities were compared with those of identical proteins from nontreated
G T Javor et al.
Journal of bacteriology, 170(7), 3291-3293 (1988-07-01)
Mu dX(lac) insertion mutants of Escherichia coli CSH50 in which the expression of the lacZ gene was sensitive to the presence of exogenous 1-thioglycerol or dithiothreitol were isolated. Both stimulatory and inhibitory mutants were found. The existence of several thiol-sensitive
L Tang et al.
Journal of biomedical materials research, 41(2), 333-340 (1998-06-25)
Biomaterial-mediated complement activation repeatedly has been invoked as a trigger of phagocyte reactions and inflammation. However, a direct correlation between complement activation and inflammatory responses to biomaterial surfaces has yet to be established. Using an animal implantation model and gold
C Unni et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 71(4), 1402-1407 (2008-06-11)
Nanoparticles of CdS were prepared at 303 K by aqueous precipitation method using CdSO4 and (NH4)2S in presence of the stabilizing agent thioglycerol. Adjustment of the thioglycerol (T) to ammonium sulphide (A) ratio (T:A) from 1:25 to 1:3.3 was done
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