I117

R(+)-IAA-94

≥98% (HPLC), solid

• Synonyme(s) : Indanyloxyacetic acid 94, R(+)-Methylindazone, R(+)-[(6,7-Dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1H-inden-5-yl)-oxy]acetic acid
• Formule empirique (notation de Hill) : C₁₇H₁₈Cl₂O₄
• Numéro CAS: 54197-31-8
• Poids moléculaire : 357.23
• Code UNSPSC : 12352200
• ID de substance PubChem : 24277844
• Nomenclature NACRES : NA.77

Propriétés

• Essai: ≥98% (HPLC)
• Forme: solid
• Activité optique: [α]22/D +36.4°, c = 0.86 in methanol(lit.)
• Couleur: white
• Solubilité: H₂O: 0.2 mg/mL; 0.1 M NaOH: 2.8 mg/mL; DMSO: >20 mg/mL; ethanol: 20 mg/mL; dilute aqueous acid: insoluble
• Température de stockage: 2-8°C
• Chaîne SMILES: C[C@@]1(Cc2cc(OCC(O)=O)c(Cl)c(Cl)c2C1=O)C3CCCC3
• InChI: 1S/C17H18Cl2O4/c1-17(10-4-2-3-5-10)7-9-6-11(23-8-12(20)21)14(18)15(19)13(9)16(17)22/h6,10H,2-5,7-8H2,1H3,(H,20,21)/t17-/m1/s1
• Clé InChI: RNOJGTHBMJBOSP-QGZVFWFLSA-N

Description

Application

R(+)-IAA-94 has been used as a chloride ion channel inhibitor to study its effects on grepafloxacin uptake by human mononuclear (THP-1) cells [1]. It has also been used as a chloride ion channel inhibitor to study its effects on moxifloxacin uptake by human mononuclear (THP-1) cells.[2]

Caractéristiques et avantages

This compound is featured on the Chloride Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)