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G3651

Sigma-Aldrich

α-Glucosidase from Bacillus stearothermophilus

greener alternative

lyophilized powder, ≥50 units/mg protein

Synonyme(s) :

α-D-Glucoside glucohydrolase, Maltase

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About This Item

Numéro CAS:
9001-42-7
Numéro de classification (Commission des enzymes):
3.2.1.20 (BRENDA, IUBMB)
Numéro CE :
232-604-7
Numéro MDL:
MFCD00081321
Code UNSPSC :
12352204
Nomenclature NACRES :
NA.54

Forme

lyophilized powder

Activité spécifique

≥50 units/mg protein

Caractéristiques du produit alternatif plus écologique

Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Activité étrangère

β-Glucosidase, α−galactosidase and β−galactosidase ≤0.1%

Autre catégorie plus écologique

Enabling,

Maladie(s) pertinente(s)

diabetes (management of non-insulin-dependent diabetes mellitus)

Température de stockage

2-8°C

Description générale

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for energy efficiency and waste prevention when used in starch hydrolysis research. For more information see the article in biofiles.

Application

α-glucosidase is potential enzyme for the biosynthesis of complex carbohydrates.

Actions biochimiques/physiologiques

α-glucosidase hydrolyzes carbohydrates by acting on 1,4-α linkages. Inhibition of α-glucosidase is a prominent target in the management of non-insulin-dependent diabetes mellitus.

Définition de l'unité

One unit will liberate 1.0 μmole of D-glucose from p-nitrophenyl α-D-glucoside per min at pH 6.8 at 37 °C.

Forme physique

Lyophilized powder containing potassium phosphate buffer salt

Remarque sur l'analyse

Activity using maltose as substrate at pH 6.0 at 25 deg C is ~2X greater than that obtained using p-nitrophenyl-α-D-glucoside as substrate at pH 6.8 at 37 °C.
Protein determined by biuret.

Autres remarques

View more information on enzymes for complex carbohydrate analysis at www.sigma-aldrich.com/enzymeexplorer

Inhibiteur

Réf. du produit
Description
Tarif

Substrat

Réf. du produit
Description
Tarif

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Arzu Coleri Cihan et al.
Cell biochemistry and function, 30(1), 69-81 (2011-10-27)
Two different α-glucosidase-producing thermophilic E134 strains were isolated from a hot spring in Kozakli, Turkey. Based on the phenotypic, phylogenetic and chemotaxonomic evidence, the strain was proposed to be a species of G. toebii. Its thermostable exo-α-1,4-glucosidases also were characterized
B Setlow et al.
Journal of applied microbiology, 120(5), 1326-1335 (2016-01-26)
This study was to determine the sources, location and identity of α-glucosidases in dormant/germinating/outgrowing spores and growing cells of Geobacillus stearothermophilus ATCC 7953, an enzymatic activity in spores used in rapid tests of steam sterilization. α-Glucosidase activity in spores and
Sanaid Ghauri et al.
3 Biotech, 11(4), 167-167 (2021-04-06)
Diabetes mellitus is a metabolic disorder of carbohydrate metabolism. The management of Diabetes mellitus with phytochemicals is hallmark of this research. Citrus species are known for their health benefits and are used as traditional food in South East Asia. The
A D Baron
Diabetes research and clinical practice, 40 Suppl, S51-S55 (1998-09-18)
Fasting blood glucose level is usually used to diagnose diabetes, but is not a good predictor of postprandial hyperglycaemia, which is a more accurate measure of the metabolic defect underlying type 2 diabetes. Postprandial blood glucose levels may be elevated
Rachel Mata et al.
Journal of natural products, 76(3), 468-483 (2013-02-13)
Type II-diabetes mellitus (TII-DM) has been regarded as one of the most important public health problems in all nations in the 21st century. Although allopathic therapies remain the most important for the initial management of TII-DM, herbal remedies have gained
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