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MAK123

Sigma-Aldrich

α-Glucosidase Activity Assay Kit

sufficient for 100 colorimetric tests

Synonyme(s) :

α-Glucosidase Test Kit

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About This Item

Code UNSPSC :
12161503
Nomenclature NACRES :
NA.84

Utilisation

sufficient for 100 colorimetric tests

Méthode de détection

colorimetric

Maladie(s) pertinente(s)

endocrinological disorders, diabetes; neurological disorders

Température de stockage

−20°C

Informations sur le gène

human ... GAA(2548)
mouse ... GAA(14387)
rat ... GAA(367562)

Catégories apparentées

Description générale

α-Glucosidase hydrolyzes carbohydrates by acting on terminal, non-reducing a(1→4)-linked D-glucose residues with the release of D-glucose. Defects in α-glucosidase have been implicated in Pompe disease and diabetes.

Application

α-Glucosidase Activity Assay Kit has been used to measure the activity of a-glucosidase.

Caractéristiques et avantages

Compatible with high-throughput handling systems.

Adéquation

Suitable for the detection of α-glucosidase activity in biological samples.

Principe

In this assay,α-glucosidase activity is determined by a reaction in which α-glucosidase hydrolyzes p-nitrophenyl-α-D-glucopyranoside resulting in the formation of a colorimetric (405 nm) product, proportional to the α-glucosidase activity present

Code de la classe de stockage

10 - Combustible liquids

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Epigallocatechin gallate affects glucose metabolism and increases fitness and lifespan in Drosophila melanogaster.
Wagner A E, et al.
Oncotarget, 6(31), 30568-30568 (2015)
Youngse Oh et al.
Molecules (Basel, Switzerland), 26(2) (2021-01-16)
Catalpa pod has been used in traditional medicine for the treatment of diabetes mellitus in South America. Studies on the constituents of Catalpa species have shown that it is rich in iridoids. In the present study, three previously undescribed compounds
Structure of human lysosomal acid a-glucosidase?a guide for the treatment of Pompe disease.
Veronique R Z, et al.
Nature Communications, 8(1), 1111-1111 (2017)
Anika E Wagner et al.
Oncotarget, 6(31), 30568-30578 (2015-09-17)
In this study, we tested whether a standardized epigallocatechin-3-gallate (EGCG) rich green tea extract (comprising > 90% EGCG) affects fitness and lifespan as well as parameters of glucose metabolism and energy homeostasis in the fruit fly, Drosophila melanogaster. Following the
Inhibitory effect of rhubarb on intestinal a-glucosidase activity in type 1 diabetic rats.
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