E6510

Ergosterol

≥75%

• Synonyme(s) : 3β-hydroxy-5,7,22-ergostatriène
• Formule empirique (notation de Hill): C₂₈H₄₄O
• Numéro CAS: 57-87-4
• Poids moléculaire : 396.65
• Numéro Beilstein : 2338604
• Numéro CE : 200-352-7
• Numéro MDL: MFCD00003623
• Code UNSPSC : 12352205
• ID de substance PubChem : 24894628
• Nomenclature NACRES : NA.77

Propriétés

• Source biologique: microbial
• Pureté: ≥75%
• Forme: powder
• Couleur: white to off-white
• Pf: 156-158 °C (lit.)
• Température de stockage: 2-8°C
• Chaîne SMILES: [H][C@@]1(CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)\C=C\[C@H](C)C(C)C
• InChI: 1S/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,26-,27-,28+/m0/s1
• Clé InChI: DNVPQKQSNYMLRS-APGDWVJJSA-N

Description

Description générale

Ergosterol or provitamin D2 is a biological precursor of Vitamin D2. It is found predominantly in cell membranes of fungi and protists such as trypanosomes.

Application

Ergosterol has been used:

• as a component of yeast cell monolayer models, to study the effects of steroidal and triterpenoid saponins on the monolayers
• as a standard sample, to isolate and identify a fungal metabolite fraction containing ergosterol
• as a component of the culture medium to isolate the CYP51^RNAi phenotype of Trypanosoma brucei gambiense, to verify ergosterol biosynthesis

Actions biochimiques/physiologiques

Ergosterol has a role in maintaining the integrity of the cell membrane and its fluidity. The sterol has anti-tumor and anti-inflammatory properties.

Informations sur la sécurité

• Mentions de danger: H413
• Conseils de prudence: P273
• Classification des risques: Aquatic Chronic 4
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges