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320269

Sigma-Aldrich

Dichlorométhane

ACS reagent, ≥99.5%, contains 40-150 ppm amylene as stabilizer

Synonyme(s) :

Chlorure de méthylène

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About This Item

Formule empirique (notation de Hill):
CH2Cl2
Numéro CAS:
75-09-2
Poids moléculaire :
84.93
Numéro Beilstein :
1730800
Numéro CE :
200-838-9
Numéro MDL:
MFCD00000881
Code UNSPSC :
12352101
ID de substance PubChem :
329753968
Nomenclature NACRES :
NA.04

Qualité

ACS reagent

Niveau de qualité

200

Agence

suitable for EPA 1613

Densité de vapeur

2.9 (vs air)

Pression de vapeur

24.45 psi ( 55 °C)
6.83 psi ( 20 °C)

Pureté

≥99.5%

Forme

liquid

Température d'inflammation spontanée

1223 °F

Contient

40-150 ppm amylene as stabilizer

Limite d'explosivité

22 %

Impuretés

Free halogens, passes test
≤0.0003 meq/g Titr. acid
≤0.02% water

Résidus d'évap.

≤0.002%

Couleur

APHA: ≤10
clear

Indice de réfraction

n20/D 1.424 (lit.)

Point d'ébullition

39.8-40 °C (lit.)

Pf

−95 °C (lit.)

Densité

1.325 g/mL at 25 °C (lit.)

Chaîne SMILES 

ClCCl

InChI

1S/CH2Cl2/c2-1-3/h1H2

Clé InChI

YMWUJEATGCHHMB-UHFFFAOYSA-N

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Application


  • Rapid and Comprehensive Analysis of 41 Harmful Substances in Multi-Matrix Products by Gas Chromatography-Mass Spectrometry Using Matrix-Matching Calibration Strategy.: This research uses gas chromatography-mass spectrometry (GC-MS) to analyze harmful substances across various matrices. Dichloromethane is employed as a solvent in the preparation phase, highlighting its application in ensuring accurate and efficient analytical results (Wang Y et al., 2024).

  • Brunonianines D-F, three new C19-diterpenoid alkaloids from the Delphinium brunonianum, with therapeutic effect on ovarian cancer in vitro and in vivo.: This study identifies new alkaloids with potential anti-cancer properties, where dichloromethane is utilized in the extraction and isolation processes. Its effectiveness in separating and preserving delicate compounds is critical for their pharmacological evaluation (Li Q et al., 2024).

  • LC-HRMS and GC-MS Profiling of Urine Free Cortisol, Cortisone, 6Β-, and 18-Hydroxycortisol for the Evaluation of Glucocorticoid and Mineralocorticoid Disorders.: Utilizes LC-HRMS and GC-MS to profile hormones in urine, with dichloromethane being crucial in the extraction process. This method ensures precision and sensitivity in hormone measurement, essential for diagnosing endocrine disorders (Casals G et al., 2024).

  • Determination of vancomycin and meropenem in serum and synovial fluid of patients with prosthetic joint infections using UPLC-MS/MS.: Features a method to measure antibiotics in biological fluids, where dichloromethane is used to prepare samples. This study underscores the solvent′s role in achieving high resolution and detection limits in clinical diagnostics (He J et al., 2024).

Caractéristiques et avantages

ACS solvents meet or exceed the high standards of the American Chemical Society (ACS) ,with test specifications that are specialized to every compound. According to the American Chemical Society, ACS reagent grade implies that it is a substance of sufficient purity to be used in most chemical analyses or reactions.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

Health hazardExclamation mark
GHS08,GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H336,H351

Classification des risques

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Central nervous system

Code de la classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

does not flash

Point d'éclair (°C)

does not flash

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Helen Harrington et al.
Journal of visualized experiments : JoVE, (81)(81), e50608-e50608 (2013-12-05)
Culturing cells in 3D on appropriate scaffolds is thought to better mimic the in vivo microenvironment and increase cell-cell interactions. The resulting 3D cellular construct can often be more relevant to studying the molecular events and cell-cell interactions than similar
Dipyridine-chromium (VI) oxide oxidation of alcohols in dichloromethane.
Collins JC, et al.
Tetrahedron Letters, 9(30), 3363-3366 (1968)
Effect of activated carbon content in TiO2-loaded activated carbon on photodegradation behaviors of dichloromethane.
Torimoto T, et al.
Journal of Photochemistry and Photobiology A: Chemistry, 103(1), 153-157 (1997)
Angharad M Roberts et al.
Science translational medicine, 7(270), 270ra6-270ra6 (2015-01-16)
The recent discovery of heterozygous human mutations that truncate full-length titin (TTN, an abundant structural, sensory, and signaling filament in muscle) as a common cause of end-stage dilated cardiomyopathy (DCM) promises new prospects for improving heart failure management. However, realization
K E Mauck et al.
Integrative and comparative biology, 54(2), 193-209 (2014-04-22)
Recent research suggests that plant viruses, and other pathogens, frequently alter host-plant phenotypes in ways that facilitate transmission by arthropod vectors. However, many viruses infect multiple hosts, raising questions about whether these pathogens are capable of inducing transmission-facilitating phenotypes in
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