Y0000002
Chlorure d′acétylcholine
European Pharmacopoeia (EP) Reference Standard
Synonyme(s) :
ACh
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About This Item
Formule linéaire :
(CH3)3N+CH2CH2OCOCH3Cl-
Numéro CAS:
Poids moléculaire :
181.66
Numéro Beilstein :
3571875
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24
Produits recommandés
Qualité
pharmaceutical primary standard
Famille d'API
acetylcholine
Fabricant/nom de marque
EDQM
Pf
146-150 °C (lit.)
Application(s)
pharmaceutical (small molecule)
Format
neat
Température de stockage
−20°C
Chaîne SMILES
[Cl-].CC(=O)OCC[N+](C)(C)C
InChI
1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
Clé InChI
JUGOREOARAHOCO-UHFFFAOYSA-M
Informations sur le gène
human ... CHRM3(1131)
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Description générale
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Acetylcholine chloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Actions biochimiques/physiologiques
Le chlorure d′acétylcholine, injecté à raison de 20 mg/kg de poids corporel, réduit la mortalité et les taux de cytokines pro-inflammatoires plasmatiques chez des souris présentant une septicémie induite expérimentalement . Le mécanisme anti-inflammatoire cholinergique dépend probablement de l′interaction entre l′acétylcholine et les récepteurs cholinergiques α7n présents sur les monocytes, macrophages et neutrophiles, qui diminue les taux de cytokines pro-inflammatoires telles que TNF-α, IL-1β et IL-6.
Conditionnement
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Autres remarques
Sales restrictions may apply.
Produit(s) apparenté(s)
Réf. du produit
Description
Tarif
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Certificats d'analyse (COA)
Lot/Batch Number
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