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C1510000

Chlorhexidine

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

1,1′-Hexamethylenebis[5-(4-chlorophenyl)biguanide]

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50 MG
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133,00 €

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About This Item

Formule linéaire :
[-(CH2)3NHC(=NH)NHC(=NH)NHC6H4Cl]2
Numéro CAS:
55-56-1
Poids moléculaire :
505.45
Beilstein:
2826432
Numéro MDL:
MFCD00009673
Code UNSPSC :
41116107
ID de substance PubChem :
329774893
Nomenclature NACRES :
NA.24

133,00 €

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Qualité

pharmaceutical primary standard

Famille d'API

chlorhexidine

Fabricant/nom de marque

EDQM

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Pf

134-136 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1

InChI

1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34)

Clé InChI

GHXZTYHSJHQHIJ-UHFFFAOYSA-N

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Chlorhexidine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

PHR1222

Chlorhexidine acetate, Pharmaceutical Secondary Standard; Certified Reference Material

C1520000

Chlorhexidine diacetate, European Pharmacopoeia (EP) Reference Standard

C1540000

Chlorhexidine dihydrochloride, European Pharmacopoeia (EP) Reference Standard

PHR1294

Digluconate de chlorhexidine, Pharmaceutical Secondary Standard; Certified Reference Material

Y0001545

Chlorhexidine for system suitability, European Pharmacopoeia (EP) Reference Standard

1111103

Chlorhexidine acetate, United States Pharmacopeia (USP) Reference Standard

PHR1459

Chlorhexidine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

1111001

Chlorhexidine, United States Pharmacopeia (USP) Reference Standard

1111012

Chlorhexidine System Suitability Mixture, United States Pharmacopeia (USP) Reference Standard

BP068

Chlorhexidine acetate, British Pharmacopoeia (BP) Reference Standard

Pictogrammes

CorrosionEnvironment
GHS05,GHS09

Mention d'avertissement

Danger

Mentions de danger

H318,H410

Classification des risques

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

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Certificats d'analyse (COA)

Lot/Batch Number

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Carolyne Horner et al.
The Journal of antimicrobial chemotherapy, 67(11), 2547-2559 (2012-07-27)
Antiseptic agents are increasingly used for hand hygiene and skin decolonization as key tools for the prevention of healthcare-associated infections. Chlorhexidine, a divalent, cationic biguanide, has a broad spectrum of activity and is one of the most frequently used topical
Richard Price et al.
BMJ (Clinical research ed.), 348, g2197-g2197 (2014-04-02)
To determine the effect on mortality of selective digestive decontamination, selective oropharyngeal decontamination, and topical oropharyngeal chlorhexidine in adult patients in general intensive care units and to compare these interventions with each other in a network meta-analysis. Systematic review, conventional
Matthias Maiwald et al.
PloS one, 7(9), e44277-e44277 (2012-09-18)
Skin antisepsis is a simple and effective measure to prevent infections. The efficacy of chlorhexidine is actively discussed in the literature on skin antisepsis. However, study outcomes due to chlorhexidine-alcohol combinations are often attributed to chlorhexidine alone. Thus, we sought
Lennie P G Derde et al.
The Lancet. Infectious diseases, 14(1), 31-39 (2013-10-29)
Intensive care units (ICUs) are high-risk areas for transmission of antimicrobial-resistant bacteria, but no controlled study has tested the effect of rapid screening and isolation of carriers on transmission in settings with best-standard precautions. We assessed interventions to reduce colonisation
Afshin Haraji et al.
Journal of orofacial pain, 27(3), 256-262 (2013-07-25)
To assess the effects of intra-alveolar application of chlorhexidine gel on the incidence of alveolar osteitis (dry socket) and the severity of postsurgical pain. A total of 160 impacted mandibular third molars were extracted in 80 patients enrolled in this
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